Cranial defects
Holoprosencephaly
Spectrum of abnormalities in which loss of midline structures results in malformations of brain and face
Schizencephaly
Large clefts occur in cerebral hemispheres
Meningocele, meningoencephalocele, and meningohydroencephalocele
Opening of occipital bone
Meningocele
Only meninges bulge
Meningoencephalocele
Brain and meninges bulge
Meningohydroencephalocele
Brain, meninges, and part of ventricle bulge
Anencephaly
Hydrocephalus
Characterized by an abnormal accumulation of cerebrospinal fluid within ventricular system
Microcephaly
Describes a cranial vault smaller than normal