CV Pathology

Question 1

Answer 1

Question 2

Question 3

outline the histologic evolution of nonreperfused MI

Answer 3

within the first 24 hours, hypereosinophilia occurs– after a dew days- weeks, fibroblasts and collagen strands start to get deposited.

• most infarcts that receive medical attension are reperfused to a certain extent, so therefore have to be interpreted in that context.

Question 4

myocardium gets stained blue, which indicates a ___ infarct

Answer 4

a remote infarct. Fibrosis happens after a few days-weeks, the infarct happened a little while ago.

Question 5

Question 6

Question 7

cardiomyopathy can be primary or secondary, and has 3 major categories

Answer 7

1. dilated
2. hypertrophic
3. restrictive

Question 9

for Dilated Cardiomyopathy:

Impaired contractility = ____ dysfunction

• Common etiologies include infection, drugs,
  metabolic dysfunction, pregnancy, genetic
• Dilated ventricles can cause ____ insufficiency
• Clinically have heart failure, sudden death, atrial
  fibrillation, and stroke (if intracardiac thrombi)

Answer 9

for Dilated Cardiomyopathy:

Impaired contractility = systolic dysfunction

• Common etiologies include infection, drugs,
  metabolic dysfunction, pregnancy, genetic
• Dilated ventricles can cause valvular insufficiency
• Clinically have heart failure, sudden death, atrial
  fibrillation, and stroke (if intracardiac thrombi)

Question 10

Which ventricle has dilated cardiomyopathy

Answer 10

RV

Question 11

Outline the hypertrophic cardiomyopahty etiology

Answer 11

it’s 100% genetic.

Question 12

T/F hypertrophic cardiomyopathy is the same as left ventricular hypertrophy due to hypertension

Answer 12

false. HC is genetic and there is no dilation, unlike LVHH– there is some dilation, and it’s due to a pathology

Question 13

dilated cardiomyopathy:

impaired contractility= ___ dysfunction

hypertrophic cardiomyopahty:

impaired compliance = ____ dysfunction

restrictive cardiomyopathy:
impaired compliance = ___ dysfunction

Answer 13

dilated cardiomyopathy:

impaired contractility= SYSTOLIC dysfunction

hypertrophic cardiomyopahty:

impaired compliance = DIASTOLIC dysfunction

restrictive cardiomyopathy:
impaired compliance = DIASTOLIC dysfunction

Question 14

which aspect of the heart is dilated in restrictive cardiomyopathy?

Answer 14

normal size ventricles but atria are often dilated.

Question 15

what is myocarditis and how is it classified?

Answer 15

inflammation of the myocardium

• classified based on type of inflammatory cell

Question 16

in lymphocyte myocarditis, you can see ___ ___. Outline some etiologies.

Answer 16

myocyte necrosis; clusters of lymphocytes in the myocardium.

Etiologies include: idiopathic, viral/post viral, autoimmune, drugs.

Question 17

Rheumatic heart diseases causes dysfunction of the ___

Answer 17

valves.

• stenosis, insufficiency, fibrotic/scarred, thickened/fused chordae and papillary muscle, or fish mouth appearance.

Question 18

most common cardiac tumor

Answer 18

cardiac myxoma is the most common cacrdiac tumor.

Question 19

which aspect of the heart is affected most frequently by cardiac myxoma?

Answer 19

LA>RA.