DCA 3 Flashcards

(100 cards)

1
Q

amoxicillin brand name

A

Amoxil, Trimox

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2
Q

Amoxil, Trimox generic name

A

amoxicillin

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3
Q

amoxicillin category

A

anti-infective

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4
Q

amoxicillin DEA

A

no

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5
Q

amoxicillin therapeutic class

A

beta-lactam antibiotic

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6
Q

amoxicillin dosage forms

A
  • tablet
  • tablet ER
  • capsule
  • chewable tablet
  • oral suspension
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7
Q

amoxicillin common indications

A
  • acute otitis media
  • lower respiratory tract infection
  • pharyngitis, tonsilitis
  • ear, nose, and throat infection
  • infection of genitourinary system
  • H. pylori GI tract infection
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8
Q

amoxicillin efficacy monitoring parameters

A

resolution of clinical signs of infection

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9
Q

amoxicillin MOA

A

Penicillin derivative that inhibits the biosynthesis of bacterial cell walls. Typically active against Streptococcus, Enterococcus, Staphylococcus, and Enterobacteriaceae

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10
Q

amoxicillin patient consultation

A
  • complete full course of therapy
  • suspension: shake well and refrigerate
  • may take with food if stomach upset occurs
  • may decrease effectiveness of oral contraceptives, use backup method
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11
Q

amoxicillin w clavulanate brand name

A

Augmentin

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12
Q

Augmentin generic name

A

amoxicillin w clavulanate

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13
Q

amox clav category

A

anti-infective

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14
Q

amox clav DEA

A

no

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15
Q

amox clav therapeutic class

A

beta-lactam antibiotic

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16
Q

amox clav dosage forms

A
  • tablet
  • tablet ER
  • capsule
  • chewable tablet
  • oral suspension
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17
Q

amox clav common indications

A
  • acute otitis media
  • commonly acquired pneumonia
  • lower respiratory infection
  • sinusitis
  • skin and soft tissue infection
  • infection of genitourinary system
  • UTI. acute cytitis
  • UTI, pyelonephritis
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18
Q

amox clav efficacy monitoring parameters

A

resolution of clinical signs of infection

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19
Q

amox clav MOA

A
  • amoxicillin is not effective against beta-lactamase producing bacteria
  • clavulanate, a beta-lactamase inhibitor has weak antibacterial activity, but is a potent inhibitor of beta-lactamase and proctects amoxicillin from degradation
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20
Q

amox clav patient consultation

A
  • complete full course of therapy
  • suspension: shake well and refrigerate
  • take dose with food to ensure proper absorption
  • may decrease effectiveness of oral contraceptives, use backup method
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21
Q

ciprofloxacin brand name

A

Cipro

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22
Q

Cipro generic name

A

ciprofloxacin

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23
Q

ciprofloxacin category

A

anti-infective

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24
Q

ciprofloxacin DEA

A

no

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25
ciprofloxacin therapeutic class
floroquinolone antibiotic
26
ciprofloxacin dosage forms
- oral suspension - oral tablet - oral tablet: ER - injectable
27
ciprofloxacin common indications
- UIT: pyelonephritis - bacterial prostatitis - antrax: postexposure prophylaxis
28
ciprofloxacin efficacy monitoring parameters
resolution of clinical signs of infection
29
ciprofloxacin MOA
a fluoroquinolone that inhibits bacterial DNA gyrase. It is highly active against aerobic gram negative bacilli and atypical bacteria
30
ciprofloxacin patient consultation
- seek medical attention of tendon pain, muscle weakness, pins and needles, numbness in arms and legs, confusion or hallucinations - take with or without food, but not with milk or other dairy products - take at least 2 hours before, or 6 hours after antacids, sucralfate or mineral supplements and vitamins with Al, Ca, Mg, Fe, or Zn
31
levofloxacin brand name
Levaquin
32
Levaquin generic name
levofloxacin
33
levofloxacin category
anti-infective
34
levofloxacin DEA
no
35
levofloxacin therapeutic class
fluoroquinolone antibiotic
36
levofloxacin dosage forms
- oral solution - oral tablet - injectable
37
levofloxacin common indications
- UTI: pyelonephritis - bacterial prostatitis - bronchitis: lower respiratory tract infection - sinusitis: upper respiratory tract infection - community acquired pneumonia
38
levofloxacin efficacy monitoring parameters
resolution of clinical signs of infection
39
levofloxacin MOA
a fluoroquinolone that inhibits bacterial DNA gyrase. It is highly active against aerobic gram negative bacilli and atypical bacteria
40
levofloxacin patient consultation
- seek medical attention of tendon pain, muscle weakness, pins and needles, numbness in arms and legs, confusion or hallucinations - take with or without food, but not with milk or other dairy products - take at least 2 hours before, or 6 hours after antacids, sucralfate or mineral supplements and vitamins with Al, Ca, Mg, Fe, or Zn
41
fluconazole brand name
Diflucan
42
Diflucan generic name
flucanozole
43
flucanozole category
anti-infective
44
fluconazole DEA
no
45
fluconazole therapeutic class
Imidazole anti fungal
46
fluconazole dosage forms
- oral suspension - oral tablet - injectable
47
fluconazole common indications
- candidal vulvavaginitis - candidiasis: systemic - oropharyngeal candidiasis
48
fluconazole efficacy monitoring parameters
resolution of clinical signs of infection
49
fluconazole MOA
inhibits biosynthesis of ergosterol and other sterols, damaging the fungal cell wall membrane and altering its permeability
50
fluconazole patient consultation
- many medications including OTC interact with flucanozole. Do not take any new medications without consulting your doctor or pharmacist - if taking weekly dose, take same time each week - suspension: shake well and store at room temp
51
nystatin brand name
Nystop, Mycostatin
52
Nystop, Mycostatin generic name
nystatin
53
nystatin category
anti-infective
54
nystatin DEA
no
55
nystatin therapeutic class
Polyene antifungal
56
nystatin dosage forms
- topical cream - topical ointment - topical powder - oral suspension
57
nystatin common indications
- candidiasis of skin - oral candidiasis
58
nystatin efficacy monitoring parametes
resolution of clinical symptoms
59
nystatin MOA
binds to the sterols in fungal cell walls, damaging fungal cell wall membrane and altering its permeability allowing for leakage of cellular contents
60
nystatin patient consultation
- apply to infected area of skin - suspension: shake well and store at room temp - do not get in eyes, nose or mouth - avoid occlusive clothing or tight fitting diapers on children
61
clindamycin brand name
Cleocin
62
Cleocin generic name
clindamycin
63
clindamycin category
anti-infective
64
clindamycin DEA
no
65
clindamycin therapeutic class
Lincosamide antibiotic
66
clindamycin dosage forms
- oral capsule - oral suspension - injectable
67
clindamycin common indications
- infection of skin or subcutaneous tissue - abdominal infection - pelvic inflammatory disease - osteomyelitis - diabetic foot infection
68
clindamycin efficacy monitoring parameters
resolution of clinical signs of infection
69
clindamycin MOA
inhibits bacterial protein synthesis by binding to the 50S ribosome subunit. It is active against most gram positive organisms except enterococci and C. difficile. Gram negative and some anaerobic gram negative are resistant
70
clindamycin patient consultation
- complete full course of therapy - take with full glass of water and remain upright for 30 min after dose to minimize risk of GI ulceration - suspension: shake well and store at room temp
71
azithromycin brand name
Zithromax, Z-max, Z-pak
72
Zithromax, Z-max, Z-pak generic name
azithromycin
73
azithromycin category
anti-infective
74
azithromycin DEA
no
75
azithromycin therapeutic class
macrolide antibiotic
76
azithromycin dosage forms
- oral tablet - oral suspension - injectable
77
azithromycin common indications
- acute infective exacerbation of COPD - sinusitis: upper respiratory tract infection - community acquired pneumonia - atypical pneumonia - STI - streptococcal pharyngitis
78
azithromycin efficacy monitoring parameters
resolution of clinical signs of infection
79
azithromycin MOA
binds to 50S ribosomal subunit, thus interfering with microbial protein synthesis, provides coverage against atypical bacteria
80
azithromycin
- complete full course of therapy - take tablets with or without food, increased tolerability with food - suspension: shake well, store at room temp
81
Flagyl, Metrogel generic name
metronidazole
82
metronidazole brand name
Flagyl, Metrogel
83
metronidazole category
anti-infective
84
metronidazole DEA
no
85
metronidazole therapeutic class
Nitroimidazole antibiotic, antiprotozoal
86
metronidazole dosage forms
- oral capsule - oral tablet - injectable - vaginal gel
87
metronidazole common indicaitons
- Abscess, anaerobic - amebic dysentery, Gardiasis - bacterial vaginosis - trichomoniasis
88
metronidazole efficacy monitoring parameters
resolution of clinical signs of infection
89
metronidazole MOA
bactericidal against nearly all obligate anaerobic bacteria
90
metronidazole patient consultation
- avoid alcohol while taking this med and for three days after, may cause severe disulfiram like reaction - complete full course of therapy - may be administered with food to avoid stomach upset
91
nitrofurantoin brand name
Macrodanit, Microbid
92
Macrodantin, Mecrobid generic name
nitrofurantoin
93
nitrofurantoin category
anti-infective
94
nitrofurantoin DEA
no
95
nitrofurantoin therapeutic class
Nitrofuran antibiotic
96
nitrofurantoin dosage forms
oral capsule
97
nitrofurantoin common indications
UTI treatment and prophylaxis
98
nitrofurantoin efficacy monitoring parameters
resolution of clinical signs of infection
99
nitrofurantoin MOA
inactivates bacterial ribosomes and is bactericidal in urine at therapeutic doses. It is active against nearly all bacteria that cause UTI's
100
nitrofurantoin patient consultation
- may make urine brown, not harmful, breakdown product of drug - complete full course of therapy