DCA 4 Flashcards

(100 cards)

1
Q

cephalexin brand name

A

Keflex

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2
Q

Keflex generic name

A

cephalexin

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3
Q

cefalexin category

A

anti-infective

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4
Q

cefalexin DEA

A

no

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5
Q

cefalexin therapeutic class

A

first generation cephalosporin

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6
Q

cefalexin dosage forms

A
  • oral suspension
  • oral tablet
  • oral capsule
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7
Q

cefalexin common indications

A
  • infection of skin or subcutaneous tissue
  • osteomyelititis
  • UTI
  • Impetigo
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8
Q

cefalexin efficacy monitoring parameters

A

resolution of clinical signs of infection

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9
Q

cefalexacin MOA

A

inhibits bacterial wall synthesis by binding to penicillin binding proteins. Primarily active against gram +ve

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10
Q

cefalexacin patient consultation

A
  • complete full course of therapy
  • suspension: shake well and store in fridge
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11
Q

cefuroxime brand name

A

Ceftin

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12
Q

Ceftin generic name

A

cefuroxime

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13
Q

cefuroxime category

A

anti-infective

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14
Q

cefuroxime DEA

A

no

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15
Q

cefuroxime therapeutic class

A

2nd gen cephalosporin

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16
Q

cefuroxime dosage forms

A
  • oral tablet
  • oral suspension
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17
Q

cefuroxime common indications

A
  • acute infective exacerbation of COPD
  • sinusitis
  • acute otitis media
  • bronchitis
  • community acquired pneumonia
  • pharyngitis, tonsillitis
  • UTI
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18
Q

cefuroxime EMP

A

resolution of clinical signs of infection

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19
Q

cefuroxime MOA

A

activity against H. influenzae, including beta lactamase producing strains. Activity against anaerobes is poor. Similar to first gen

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20
Q

cefuroxime patient consultation

A
  • complete full course of therapy
  • suspension: shake well and store in fridge
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21
Q

cefdinir brand name

A

Omnicef

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22
Q

Omnicel generic name

A

cefdinir

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23
Q

cefdinir category

A

anti-infective

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24
Q

cefdinir DEA

A

no

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25
cefdinir therapeutic class
3rd generation cephalosporin
26
cefdinir dosage form
- oral suspension - oral capsule
27
cefdinir common indications
- acute otitis media - bronchitis - community acquired pneumonia - acute infective exacerbation of COPD
28
cefdinir EMP
resolution of clinical signs of infectio
29
cefdinir MOA
active against many gram +ve and some gram -ve. Active agains beta-lactamase producing strains
30
cefdinir patient consultation
- complete full course of therapy - suspension: shake well and store at room temp - separate from antacids, iron, and vitamin products for at least two hours
31
trimethoprim / sulfamethoxazole brand name
Bactrim / Septra
32
Bactrim / Septra generic name
trimethoprim / sulfamethoxazole
33
trimethoprim category
anti-infective
34
trimethoprim DEA
No
35
trimethoprim therapeutic class
Sulfonamide antibiotic
36
trimethoprim dosage forms
- oral tablet - oral suspension - injectable
37
trimethoprim common indications
- Staphylococcal infection of skin - pneumocystis - UTI
38
trimethoprim EMP
- resolution of clinical signs of infections - decreased episodes of pneumocystis pneumonia
39
trimethoprim MOA
SMZ competitively inhibits the synthesis of folic acid precursors. TMP inhibits the enzymatic reduction of dihydrofolic acid to tetrahydrofolic acid
40
trimethoprim patient cosultation
- complete full course of therapy - suspension: shake well and store at room temp, protect from light - may cause photosensitivity - maintain adequate hydration to avoid kidney complications
41
doxycycline brand name
Vibramycin
42
Vibramycin generic name
doxycycline
43
doxycycline category
anti-infective
44
doxycycline DEA
no
45
doxycycline therapeutic class
tetracycline antibiotic
46
doxycycline dosage forms
- oral tablet - oral capsule - oral injectable
47
doxycycline common indications
- staphylococcal infection of skin - community acquired pneumonia - Chlamydia infections - Tick-borne diseases
48
doxycycline EMP
resolution of clinical sign of infection
49
doxycycline MOA
broad spectrum bacteriostatic compound that inhibits protein synthesis at the 30S ribosomal subunit. Activity includes gram +ve, gram -ve, aerobic, anaerobic and atypical
50
doxycycline patient consultation
- sit upright for 30 min after taking oral dose to avoid esophageal injury. Make take with food that does not contain calcium. - complete full course of therapy - may cause photosensitivity - take with plenty of water
51
minocycline brand name
Minocin
52
Minocin generic name
minocycline
53
minocycline category
anti-infective
54
minocycline DEA
no
55
minocycline therapeutic class
tetracycline antibiotic
56
minocycline common indications
- acne vulgaris - staphylococcus infection of skin
57
minocycline dosage forms
- oral tablet - oral capsule - oral tablet ER - oral capsule ER 24 hr - injectable
58
minocycline EMP
- resolution of clinical sign of infection - decreased acne
59
minocycline MOA
broad spectrum bacteriostatic compound that inhibits protein synthesis at the 30S ribosomal subunit. Activity includes gram +ve, gram -ve, aerobic, anaerobic and atypical
60
minocycline patient consultation
- may take with food that does not contain calcium - complete full course of therapy - warn patients to avoid pregnancy
61
mupirocin brand name
Bactroban
62
Bactroban generic name
mupirocin
63
mupirocin category
anti-infective
64
mupirocin DEA
no
65
mupirocin therapeutic class
topical antibacterial
66
mupirocin dosage forms
- topical cream - topical ointment - nasal ointment
67
mupirocin common indications
- impetigo - eradication of nasal colonization of MRSA
68
mupirocin EMP
- resolution of clincal sign of infection - eradication of MRSA
69
mupirocin MOA
active against a wide range of gram +ve bacteria including MRSA
70
mupirocin patient consultation
- instruct patient on correct application - avoid drug exposure to open wounds, eyes or burns
71
acyclovir brand name
Zovirax
72
Zovirax generic name
acyclovir
73
acyclovir category
anti-infective
74
acyclovir DEA
no
75
acyclovir therapeutic class
Viral DNA polymerase inhibitor
76
acyclovir dosage forms
- oral tablet - oral capsule - oral suspension - injectable
77
acyclovir common indications
- genital herpes - herpes zoster - Varicella - cold sores
78
acyclovir EMP
resolution of clinical signs of infection within 2-3 days
79
acyclovir MOA
competatively inhibits viral DNA synthesis by inactivation of viral DNA polymerase and through incorporation into and termination of viral DNA replication
80
acyclovir patient consultation
- complete full course of therapy - ensure adequate hydration - initiate treatment as soon as possible at first sign of herpes, lesion or varicella rash - Suspension: shake well and store at room temp
81
valcyclovir brand name
Valtrex
82
Valtrex generic name
valcyclovir
83
valcyclovir category
anti-infective
84
valcyclovir DEA
no
85
valcyclovir therapeutic class
Viral DNA polymerase inhibitor
86
valcyclovir dosage forms
oral tablet
87
valcyclovir common indications
- genital herpes - herpes zoster - varicella - cold sores
88
valcyclovir EMP
resolution of clincial signs of infection
89
valacyclovir MOA
prodrug of acyclovir with the same MOA
90
valacyclovir patient consultation
- if using for prophylaxis, this med should reduce number of breakouts - maintain adequate hydration
91
oseltamivir brand name
Tamiflu
92
Tamiflu generic name
oseltamivir
93
oseltamivir category
anti-infective
94
oseltamivir DEA
no
95
oseltamivir therapeutic class
Neuraminidase inhibitor, antiviral
96
oseltamivir dosage forms
- oral capsule - oral suspension
97
oseltamivir common indications
Influenze type A and B
98
oseltamivir EMP
prevention or resolution of influenza infection
99
oseltamivir MOA
inhibitor of influenza virus neuraminadase, which prevents viral progeny from detaching from the cellular envolope
100
oseltamivir patient consultaiton
- complete full course of therapy - take with food to minimize GI irritation - take missed dose as soon as possible, if next dose is within two hours, skip - suspension: shake well and store at room temp