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DCA 8 Flashcards

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1
Q

fluticasone brand name

A
  1. ArmonAir
  2. ArmonAir Respiclick
  3. Arnuity Ellipta
  4. Flovent Diskus
  5. Flovent HFA, Flonase
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2
Q
  1. ArmonAir
  2. ArmonAir Respiclick
  3. Arnuity Ellipta
  4. Flovent Diskus
  5. Flovent HFA, Flonase
    generic name
A

fluticasone

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3
Q

fluticasone therapeutic class

A

Inhaled Adrenal Corticosteroid

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4
Q

fluticasone dosage forms

A
  • MDI
  • Aerosol powder for inhalation - Nasal spray
  • Nasal exhaler suspensio
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5
Q

fluticasone common indications

A
  • Asthma
  • Nonallergic rhinitis
  • Nasal polyps - Allergic rhinitis
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6
Q

fluticasone EMP

A
  • Control of asthma, as measured by pulmonary function tests
  • Frequency of asthma exacerbations
  • Need for rescue inhaler use - Control of rhinitis signs and symptoms
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7
Q

fluticasone MOA

A

a synthetic trifluorinated corticosteroid with anti-inflammatory effects. It is a human glucocorticoid receptor agonist that inhibits multiple cell types and mediator production or secretion involved in asthma. Fluticasone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2-inhibitory proteins, lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2

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8
Q

fluticasone patient consultaiton

A
  • Instruct on proper inhaler and nasal spray administration technique
  • Rinse mouth after each use to prevent oral infections
  • Monitor for oral candidiasis - Inform patient there may be a scent associated with this product
  • Relief and/or adverse effects may not occur for several days after inhalation
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9
Q

fluticasone/umeclidinium/vilanterol brand name

A

Trelegy Ellipta

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10
Q

Trelegy Elipta generic name

A

fluticasone/umeclidinium/vilanterol

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11
Q

fluticasone/umeclidinium/vilanterol therapeutic class

A

Inhaled Adrenal Corticosteroid (ICS)/Anticholinergic/Long Acting Beta 2 Adrenergic Agonist (LABA)

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12
Q

fluticasone/umeclidinium/vilanterol common indications

A
  • COPD
  • asthma
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13
Q

fluticasone/umeclidinium/vilanterol dosage forms

A

DPI

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14
Q

fluticasone/umeclidinium/vilanterol EMP

A
  • Control of asthma or COPD symptoms, as measured by pulmonary function tests
  • frequency or asthma or COPD exacerbations
  • Need for rescue inhaler use
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15
Q

fluticasone/umeclidinium/vilanterol MOA

A

Fluticasone furoate provides anti-inflammatory activity via activation of the glucocorticoid response element, inhibiting pro-inflammatory transcription factors, and inhibition of antigen-induced lung eosinophilia. Umeclidinium inhibits the M3 receptor in the smooth muscles of the airway, leading to bronchodilation. Vilanterol increases cyclin adenosine monophosphate levels, which causes the bronchial smooth muscles to relax and inhibition of release of mediators of immediate hypersensitivity from cells

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16
Q

fluticasone/umeclidinium/vilanterol patient consultation

A
  • Advise patient that drug is not to be used to relieve acute symptoms and extra doses should not be used for that purpose. Instruct patient to treat acute symptoms with a short-acting beta-agonist rescue inhaler
  • Instruct patient not to exceed maximum recommended dose of 1 inhalation/day
  • Advise patient to rinse mouth with water (do not swallow) after use to reduce risk of oropharyngeal candidiasis
  • Encourage patient to avoid abrupt discontinuation - Warn patient to report symptoms of an infection, hypercorticism, or adrenal suppression
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17
Q

fluticasone/vilanterol brand name

A

Breo Ellipta

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18
Q

Ellipta generic name

A

fluticasone/vilanterol

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19
Q

fluticasone/vilanterol patient consultation

A
  • Advise patient that drug is not to be used to relieve acute symptoms and extra doses should not be used for that purpose. Instruct patient to treat acute symptoms with a short-acting beta-agonist rescue inhaler
  • Instruct patient not to exceed maximum recommended dose of 1 inhalation/day
  • Advise patient to rinse mouth with water (do not swallow) after use to reduce risk of oropharyngeal candidiasis
  • Encourage patient to avoid abrupt discontinuation - Warn patient to report symptoms of an infection, hypercorticism, or adrenal suppression
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20
Q

fluticasone/vilanterol therapeutic class

A

Inhaled Adrenal Corticosteroid (ICS)/Long Acting Beta 2 Adrenergic Agonist (LABA)

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21
Q

fluticasone/vilanterol dosage forms

A

DPI

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22
Q

fluticasone/vilanterol common indications

A
  • COPD
  • asthma
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23
Q

fluticasone/vilanterol EMP

A
  • Control of asthma or COPD symptoms, as measured by pulmonary function tests
  • frequency or asthma or COPD exacerbations
  • Need for rescue inhaler use
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24
Q

fluticasone/vilanterol MOA

A

Fluticasone furoate provides anti-inflammatory activity via activation of the glucocorticoid response element, inhibiting pro-inflammatory transcription factors, and inhibition of antigen-induced lung eosinophilia. Vilanterol increases cyclin adenosine monophosphate levels, which causes the bronchial smooth muscles to relax and inhibition of release of mediators of immediate hypersensitivity from cells

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25
fluticasone with salmeterol brand name
Advair Diskus, Advair HFA, AirDuo Respiclick
26
Advair Diskus, Advair HFA, AirDuo Respiclick generic name
fluticasone with salmeterol
27
fluticasone with salmeterol therapeutic class
Inhaled Corticosteroid (ICS) and Long-Acting Beta-2 Adrenergic Agonist (LABA) Combination
28
fluticasone with salmeterol dosage forms
- MDI - aerosol powder for inhalation
29
fluticasone with salmeterol common indications
- asthma - COPD
30
fluticasone with salmeterol EMP
- Control of asthma or COPD symptoms, as measured by pulmonary function tests - frequency or asthma or COPD exacerbations - Need for rescue inhaler use
31
fluticasone with salmeterol MOA
Fluticasone is a synthetic trifluorinated corticosteroid with anti-inflammatory effects. It is a human glucocorticoid receptor agonist that inhibits multiple cell types and mediator production or secretion involved in asthma. Salmeterol is a long-acting β2-adrenergic agonist, stimulates intracellular adenylyl cyclase in catalyzing the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). The increased cyclic AMP levels result in the relaxation of bronchial smooth muscle and inhibition of the release of mediators of instantaneous hypersensitivity from mast cells.
32
fluticasone with salmeterol patient consultation
- Instruct on proper inhaler technique - Rinse mouth after each use to prevent oral infections - Monitor for oral candidiasis
33
budesonide brand name
- Pulmicort Respules - Pulmicort Flexhaler
34
Pulmicort Respules, Pulmicort Flexhaler brand name
budesonide
35
budesonide therapeutic class
corticosteroid
36
budesonide dosage forms
- Inhalation suspension - MDI - Topical - ER tablets - Nasal spray - Delayed release Capsules
37
budesonide common indications
- Inhalations: Asthma - - PO options: Crohns, Ulcerative colitis
38
budesonide EMP
- Monitor pulmonary function tests - Resolution of asthma symptoms (symptoms, number or exacerbations, nighttime awakenings, need for rescue albuterol)
39
budesonide MOA
Anti-inflammatory with potent glucocorticoid and weak mineralocorticoid activity. It exhibits a broad range of active inhibition against multiple cell types and mediators involving allergic and nonallergic/irritant-mediated inflammation.
40
budesonide patietnt consultation
- Instruct on proper inhalation technique -Gently swirl nebulizer suspension before use. - Use entire vial of inhalation suspension immediately after opening to avoid contamination; deliver over 5-15 min using a jet nebulizer with mouthpiece or face mask. After administration, rinse mouth with water, spit, and was face to minimize risk of developing oral candidiasis - Provided as a strip of five small plastic containers with sealed caps; each container holds 1 dose. The strip of containers is sealed inside a foil pouch. Keep any unused containers inside the pouch. Once foil pouch is opened, the containers will only be good for 2 wk.
41
budesonide with formoterol (inhalation) brand name
42
Symbicort generic name
budesonide with formoterol (inhalation)
43
budesonide with formoterol (inhalation) therapeutic class
Inhaled Corticosteroid (ICS)/Long acting Beta agonist (LABA) Combination
44
budesonide with formoterol (inhalation) dosage forms
MDI
45
budesonide with formoterol (inhalation) common indications
- asthma - COPD
46
budesonide with formoterol (inhalation) EMP
- Monitor pulmonary function tests - Resolution of asthma symptoms (symptoms, number or exacerbations, nighttime awakenings, need for resuce albuterol)
47
budesonide with formoterol (inhalation) MOA
Budesonide is an anti-inflammatory with potent glucocorticoid and weak mineralocorticoid activity. It exhibits a broad range of active inhibition against multiple cell types and mediators involving allergic and nonallergic/irritant-mediated inflammation. Formoterol is a long-acting selective β2-adrenergic agonist that produces bronchodilation.
48
budesonide with formoterol (inhalation) patient consultation
- Instruct on proper inhalation technique - if >1 inhalation is prescribed, wait 1 min aftre initial inhalation and shake the inhaler again before the next inhalation - Rinse mouth and spit and wash face to minimize risk of developing oral candidiasis - Wash mouthpiece and air-dry thoroughly at least once a week
49
hydrocortisone brand name
Hydrocort, Solu-Cortef
50
Hydrocort, Solu-Cortef generic name
hydrocortisone
51
hydrocortisone therapeutic class
Topical and Systemic Corticosteroid
52
hydrocortisone dosage forms
- Rectal Cream - Rectal Enema - Rectal Foam - Topical Cream - Topical Lotion - Topical Ointment - Oral tablet - IV injection
53
hydrocortisone common indications
- Allergic states - Adrenal insufficiency - Eye disorders - GI disorders - Skin disorders - Respiratory diseases - Inflammatory musculoskeletal disorders
54
hydrocortisone EMP
improvement of clinical signs of disorder
55
hydrocortisone MOA
Hydrocortisone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2-inhibitory proteins, lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2
56
hydrocortisone patient consultation
- Apply thin layer to affected area of skin - Skin should be clean and intact at site of application - Wash hands before and after application - Avoid contact with eyes and do not ingest by mouth - Avoid occlusive dressings or tight-fitting clothers over site of administration
57
prednisolone brand name
Orapred, Pediapred
58
Orapred, Pediapred generic name
prednisolone
59
prednisolone therapeutic class
Adrenal Glucocorticosteroid
60
prednisolone dosage forms
- Oral tablet IR - Oral dispersible tablet - Oral solution
61
prednisolone common indications
- Allergic states - Dematologic diseases - Endocrine disorders - GI diseases - Hematologic disorders - Respiratory diseases - Rheumatic disorders
62
prednisolone EMP
Improvement or Resolution of clinical signs and symptoms
63
prednisolone MOA
Glucocorticosteroids are naturally occurring and synthetic adrenocortical steroids that cause varied metabolic effects, modify the body’s immune responses to diverse stimuli, and are used primarily for their anti-inflammatory effects in disorders of many organ systems. Prednisolone is the active form of prednisone.
64
prednisolone patient consultation
- Take with food or mild to prevent GI upset - Take in the morning to prevent insomnia - Have patients monitor for signs of hyperglycemia, osteoporosis, adrenocortical insufficiency, and infection with long-term use
65
triamcinolone brand name
Kenalog
66
Kenalog
triamcinolone
67
triamcinolone therapeutic class
topical corticosteroid
68
triamcinolone dosage forms
- Cream - Lotion - Ointment - Aerosol Solution
69
triamcinolone common indications
skin disorders
70
triamcinolone EMP
improvement of clinical signs of skin disorders
71
triamcinolone MOA
Triamcinolone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.
72
triamcinolone patient consultation
- Apply thin layer to affected area - Skin should be clean and intact at site of application - Wash hands before and after application - Avoid contact with eyes and do not ingest by mouth - Avoid occlusive dressings or tight-fitting clothers over site of administration
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