What parts do enzymes consist of
apoenzyme = protein
Cofactor = non protein part, may be metal ion or organic molecule such as coenzyme
3 properties of enzymes
Specific
Subject to a variety of controls
efficient
why are enzymes specific
Each enzymes binds to specific substrates.
Lock and key = active site fits to substrate (key)
Induced fit= active site changes to fit closely around substrate
Why are enzymes efficient
Speed up rate of reaction by lowering activation energy
why are enzymes subject to a variety of cellular controls
Their rate of synthesis and concentration at any given time is under control of cells genes. Substances within the cell may enhance or inhibit the enzyme at any given time
The rate at which the active form of enzyme can become inactive is determined by chemical environment of cell
How do enzymes decrease activation energy?
Bring substrates together in the correct orientation, so that reactions can occur.
*They can catalyse reversible reactions
1st stage of how enzyme works
The substrate makes contact with the enzymes active site forming a temporary compound called the enzyme substrate complex
2nd stage of how enzyme works
Substrate is transformed by the rearrangement of atoms
Breakdown of substrate or combination of substrate molecules
3rd stage of how enzyme works
Substrate unbind from enzyme and the unchanged enzyme is free to attach to another substrate