Genome Projects

Question 1

What do genome projects aim to determine?

Answer 1

The entire base sequence of an organisms DNA

Question 2

What do genome projects help identify?

Answer 2

The location and sequence of genes

Question 3

What do genome projects help understand?

Answer 3

The genetic basis of diseases

Question 4

What do genome projects help to develop?

Answer 4

Diagnostics, treatments and vaccines

Question 5

Prokaryotes?

Answer 5

No introns- no splicing
Genes are usually not regulated and are all expressed
Therefore the genome directly determines the proteome

Question 6

Application of genome projects in prokaryotes?

Answer 6

Helps identify potential antigens for vaccine development

Question 7

Why is predicting the entire proteome difficult in complex organisms e.g. humans?

Answer 7

Genes contain introns
Genes may be turned on or off in different tissues or at different times
Alternative splicing can create multiple proteins from one gene