Glucagon

Question 1

Glucagon classification

Answer 1

Anti-hypoglycemic agent/hormone

Question 2

Glucagon action

Answer 2

1. Increase BG by converting the liver glycogen to glucose

2. Relax smooth muscle of stomach, duodenum, small bowel and colon

Question 3

Glucagon onset and duration

Answer 3

1. IV 1 min, IM 10 min

2. IV 25 min, IM 30 min

Question 4

Glucagon indication

Answer 4

1. BG< 80, if IV access is difficult
2. Beta blocker or calcium channel blocker overdose
3. Foreign body obstruction in esophagus

Question 5

Glucagon contraindication

Answer 5

Hypersensitivity

Question 6

Glucagon precautions

Answer 6

1. Liver, renal or CVD

2. Starvation

Question 7

Glucagon dosage and administration

Answer 7

1. Obtain Dexi
2. Adult:
   a. Hypoglycemia: 1mg IM
   b. Beta blocker OD: 3-10mg IV slowly over 3-5 min
3. Pediatric:
   a. 20kg give 1mg IM

Question 8

Glucagon Adverse Reaction

Answer 8

V/V, Allergic Reaction, HA, Hypertension, Dizziness

Question 9

Glucagon reference in protocol

Answer 9

Medical (ALOC, OD on beta blocker)