Thiamine Class
Vitamin B
Thiamine Action
Combines with ATP to form thiamine pyrophosphate coenzyme for carbohydrate metabolism. Brain is extremely sedative to thiamine deficiency
Thiamine Onset and Duration
Onset: Rapid
Peak: Variable
Duration: Depends on degree of deficiency
Thiamine Indications
Coma, Delirium Tremens, beriberi, Wernickie encephalopathy
Thiamine Contraindications
Give Thiamine before glucose under all circumstances
Thiamine Dosage and Administration
Adult: 100mg slow IV/IM
Per: 10-25mg slow IV/IM
Thiamine Adverse Reactions
Anxiety, dyspnea, vasodilation, hypotension, N/V