What are the 3 components of a nucleotide
Deoxyribs sugar
Phosphate molecule
Base
Scientists that discovered DNA
Franklin- provided x-ray images
Watson
Crick
2 Functions of DNA
Genetic code are segments of DNA that hold specific instructions.
Replication- cells divide to create new cells
What is a genome?
Complete set of genetic material for an organism
DNA
Long molecule made up two straws which are twisted together to make a spiral-double helix. Molecule of inheritance.
How is protein synthesis carried out?
DNA unzips
Transcription (messenger is formed)
MRNA leaves the nucleus and enters the cytoplasm.
TRNA s attached to a specific amino acid
TRNA binds to MRNA
Phenotype
Characteristics you can see
Genotype
Genetic code ( can’t see)
What are the types of mutation of DNA base sequences?
Insertation- A new base enters the sequence where it shouldn’t be. Amino acids will change.
Deletions- Random base is deleted from the sequence which has a knock on effect.
Substitution- A random base in the sequence is changed to a different base.
Meiosis process
Parent cell
Chromosomes make identical copies of themselves.
Similar chromosomes pair up.
Sections of DNA get swapped
Pairs of chromosomes divide.
Chromosomes divide again.
Feature of meiosis
Production of sex cells
Cell divides twice, forming four gametes or daughter cells.
Gametes are genetically different.
What is Mendall’s experiment?
Take two plants; one which is pure-bred for tallness and one pure-bred for shortness and cross them.
Heterozygous
Two different alleles (Bb)
Homozygous
Two of the same alleles (BB) (bb)
Allele
Different versions of the same gene.
Cystic fibrosis and symptoms
Produce too much mucus- can use embryo screening.
Symptoms- Thick sticky mucus in airways.
Repeated chest infections
Poor digestion leading to malnutrition.
Blockage of bowels.
Fertility problems.
Artificial insemination
Only one male can fertilise many females at the same time. This allows the farmer to pick the best genes.
What is selective breeding?
What is the drawback?
Allowed the breeding of animals (working) which were obedient, fast and agile enough to do the jobs required.
It introduced many deformities through the distortion of characteristics.
What is genetic engineering?
Process where the genome of an organism is modified by introducing another gene from a different organism to give a desired characteristic.
Genetic engineering steps:
Clone
Genetically identical to the mother. Genetically identical copy of the original body cell.
Cloning steps
What are 3 advantages of cloning?
Genetically engineered animals can be cloned.
Save animals from extinction.
Produce stem cells for therapeutic purposes.
What are 3 disadvantages of cloning?
Could lead to cloning babies.
Reduced variety in population.
Research the destruction of embryos.