Ipratropium Bromide

Question 1

Ipratropium Bromide - Type

Answer 1

Anticholinergic bronchodilator

Question 2

Ipratropium Bromide - Presentation

Answer 2

250mcg in 1ml MDI delivering 21mcg per activation

Question 3

Ipratropium Bromide - Actions (3)

Answer 3

1. Bronchodilator
2. Blocks vagal reflexes which mediate bronchoconstriction
3. Possibly more effective when used in combination with salbutamol

Onset 3-5 mins, duration 2-4 hrs

Question 4

Ipratropium Bromide - Use

Answer 4

Bronchospasm from any cause, as an adjunct to salbutamol

Question 5

Ipratropium Bromide - Adverse effects

Answer 5

Rare with single dose, occasionally urinary retention

Question 6

Ipratropium Bromide - Contraindication

Answer 6

Known hypersensitivity

Question 7

Ipratropium Bromide - Precaution

Answer 7

Care needs with use in patients with glaucoma

Question 8

Ipratropium Bromide - Doses

Answer 8

Administer with every 2nd dose of salbutamol

Adult (>6 yrs) - 500mcg

• 4 x 21mcg (4 puffs)

Paediatric (<6 yrs) - 250mcg

• 2 x 21mcg (2 puffs)