Ondansetron

Question 1

Ondansetron - Type

Answer 1

Potent anti-nauseant and antiemetic

Question 2

Ondansetron - Presentation

Answer 2

4mg in 2ml

Question 3

Ondansetron - Actions (4)

Answer 3

1. Potent, highly specific and selective serotonin 5-HT receptor antagonist
2. Precise mode of action in control of nausea and vomiting is not known. Likely to have action peripherally and in the CNS
3. Maximum effect is approximately 10 min following IV admin
4. Hepatic metabolism

Question 4

Ondansetron - Use

Answer 4

For prevention or treatment of nausea and vomiting

Question 5

Ondansetron - Adverse effects (6)

Answer 5

Uncommon:

1. Headache
2. Flushing of skin
3. Occasional reaction at the site of IV injection
4. Drowsiness
5. Anxiety and agitation
6. Transient visual disturbances

Question 6

Ondansetron - Contraindication

Answer 6

Known hypersensitivity

Question 7

Ondansetron - Precaution

Answer 7

Not recommended in pregnancy

Question 8

Ondansetron - Dose

Answer 8

Adult - 4mg IM/IV (over 2 min)
Paediatric - 0.1mg/kg to max 4mg IM/IV (over 2 min)
Can rep x 1 if req