tetranucleotide hypothesis
Chargaff’s data falsified the tetranucleotide hypothesis which was there was a repeating sequence of the four bases in DNA.
his data showed amount of pyridines and purines
positive vs negative feedback
negative feedback reverses a change to bring the system back to a stable set point, crucial for maintaining internal balance (homeostasis).
while positive feedback amplifies the initial stimulus, driving a process to completion (blood clotting) away from original
intraspecies vs interspecies competition
intra is same species
inter is diff
genone vs transcriptome vs proteome
the genome is the entire DNA blueprint in a cell (same in all cells),
transcriptome is the subset of genes actively transcribed into RNA (mRNA, tRNA, rRNA) at a specific time (varies by cell type/condition),
the proteome is the complete set of proteins produced from that transcriptome,
role of promoter
non-coding DNA before a gene,
binding site for RNA polymerase and transcription factors to initiate transcription
role of telomere
is a protective, repetitive DNA sequence at the end of a chromosome
prevent DNA ends from fraying
number of h bonds for bases
a and t= 2
c and g= 3
purines vs pyridines structure
purines have a double-ring structure, while pyrimidines have a single-ring structure
what does uracil replace
thymine
alternative splicing
The selective removal of specific exons
produce variants of a protein from a single gene
codon vs anticodon
codon 3 nucleotide seqyence on mRNA specificies aa
Anticodon: 3nucleotide sequence on tRNA that bins to codon, ensuring correct aa brought to ribosome