ddx kyste complexe
IDC
carcinome papillaire
Carcinome métaplastique du sein (spindle cell) : forme IDC
DCIS
papillome
abcès
nécrose graisseuse
fibroadénome
inversion vs rétraction mamelon
pattern rehaussement N mamelon
localisation + commune sein ectopique
niveau ganglion axillaire
SELON RELATION PECTORAL MINEUR
* There are 5 groups of LN in the axilla: 3 groups in level I, which is inferolateral to the pectoralis minor; one group in level II behind the pectoralis minor; and one group superomedial to the pectoralis minor in level III. Drainage generally proceeds in a stepwise fashion from level I to level II to level III, and finally into the thorax.
nom ganglion entre pec mineur et majeur
rotter
facteur qui augmente et qui diminue densité sein
FACTEUR QUI AUGMENTE DENSITÉ
* Hormone replacement therapy: the effect is greater with combination hormone therapy than with estrogen therapy alone
* Pregnancy
* Lactation
* Weight loss (from a reduction of breast fat)
* Nullipart
* Inflammation: mastite
* Carcinoma inflammatoire du sein
FACTEUR QUI DIMINUE DENSITÉ
* Age
* Postmenopausal state
* Medications, e.g. Danazol
* Vitamin D, calcium chez préménopause
* Weight gain
* Acromégalie
quand considérer dx alternatif de gynecomastie
dépistage pour transfemin (male à female)
Transfeminine (Male-to-Female) Individuals
* Age 40–49, average risk, ≥5 years hormone use → annual mammography/DBT suggested.
* Age 50+, average risk, ≥5 years hormone use → mammography/DBT every 1–2 years suggested.
* <5 years or no hormone use → routine screening not recommended.
* High-risk transfeminine patients (e.g., BRCA mutation, chest irradiation, strong family history) → same high-risk screening protocol as cisgender women: annual mammography/DBT + MRI starting at 25–30.
depistage Transmasculine (Female-to-Male) Individuals
en gros
- si mastectomie : pas depistage, sinon
- debute 40 ans
Transmasculine (Female-to-Male) Individuals
* Under 40 : PAS dépistage ; with or without bilateral mastectomy → no routine recommended.
* Age 40–49, average risk, without bilateral mastectomy → annual mammography/DBT suggested.
* Age 50+, average risk, without bilateral mastectomy → mammography/DBT every 1–2 years recommended.
* With bilateral mastectomy (“top surgery”) → PAS DEPISTAGE, no routine screening needed regardless of age or risk.
meilleur vue pour évaluer effet accordion
sous type moleculaire neo sein avec BRCA 1 vs 2
BRCA1: more medullary and more ER/PR/HER2 (-) cancers, DCIS is rare
BRCA 2: more ER+/HER2-, more DCIS (visible calc [about 40%]); ADK pancréas; néo homme
Both: high grade, higher change of malignancy in circumscribed masses, most commonly present with a well-defined masses
complication papillomatose juvénile
FDR POUR NÉO SEIN
* Patients with bilateral and recurrent disease and a family history of breast cancer are at risk of developing subsequent breast cancer and should be closely monitored
multifocal vs multicentrique
selon > 4 CM !!
MULTIFOCAL
* Multiple (≥ 2) separate foci of breast cancer in same breast
* Separated by ≥ 0.5 cm and ≤ 4 cm, in same duct system
* Mastectomie partielle
MULTICENTRIQUE
* Multiple (≥ 2) separate foci of breast cancer where greatest distance between 2 foci is variably > 4-5 cm;
* Typically in different breast quadrants / different duct systems
* Mastectomie totale
V ou F, pash habituellement calcifié
faux
particularité bx femme enceinte
histologie tumeur phyllode
Locally aggressive biphasic tumor consisting of neoplastic intralobular-type stromal cells and benign epithelial cells
masse sein plus frequent lactation
galactocèle
- PAS FLUX DOPPLER
masse niveau gras liquide
GALACTOCÈLE
masse sein post accouchement qui presente flux
ADENOME LACTATION
- galactocele nA PAS FLUX DOPPLER
pattern rehaussement + fréquent DCIS
PATTERN REHAUSSEMENT + FRÉQUENT : NON MASS LIKE clumped nonmasslike enhancement in a ductal, linear, segmental, or regional distribution
quelle type DCIS plus agressif
MLO, lesion HAUTEUR MUSCLE PECTORAL va se localsier ou
meilleur moment pour faire IRM et mammo