Statistics NAVLE Flashcards

(16 cards)

1
Q

What does PPV stand for in the context of test statistics?

A

Positive Predictive Value

PPV indicates the proportion of test-positive animals that are truly infected or disease positive.

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2
Q

What is the NPV in test statistics?

A

Negative Predictive Value

NPV indicates the proportion of test-negative animals that are truly not infected or disease negative.

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3
Q

What are the FIP test stats for Mɸ’s in effusion fluid?

A
  • 100% PPV
  • 57% NPV

These statistics indicate the effectiveness of the test in identifying true positives and negatives.

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4
Q

What is the PPV for anti-coronavirus antibodies in serum?

A

0.44

This indicates a low positive predictive value for this specific test.

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5
Q

What is the NPV for anti-coronavirus antibodies in serum?

A

0.94

This indicates a high negative predictive value for this specific test.

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6
Q

What is the Pyramid of Evidence used for?

A
  • Filtered evidence: systematic reviews, meta-analyses, critical appraisals
  • Unfiltered evidence: randomized controlled trials, cohort studies, case reports

The pyramid illustrates the hierarchy of evidence in research.

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7
Q

What does specificity measure in a test?

A

Proportion of non-diseased animals identified as negative

Specificity can be affected by factors such as cross-reactivity and sample contamination.

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8
Q

What is the formula for calculating specificity?

A

Specificity = True negatives / (True negatives + False positives)

This formula helps determine the accuracy of a test in identifying non-diseased individuals.

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9
Q

What does sensitivity measure in a test?

A

Proportion of diseased animals identified as positive

Sensitivity can be low when there are very few amounts of the target measure or when samples are degraded.

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10
Q

What is the formula for calculating sensitivity?

A

Sensitivity = True positives / (True positives + False negatives)

This formula helps determine the accuracy of a test in identifying diseased individuals.

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11
Q

Define false positives.

A

Non-diseased animal that tests positive

This indicates a test error where a healthy individual is incorrectly identified as having the disease.

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12
Q

Define false negatives.

A

Diseased animal that tests negative

This indicates a test error where an infected individual is incorrectly identified as healthy.

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13
Q

What is the prevalence formula?

A

Prevalence = Total Disease / Total * 100

This formula calculates the proportion of a population that has a specific disease at a given time.

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14
Q

What are the characteristics of a cohort study?

A

Addresses temporality of disease causation

In cohort studies, exposure must precede the disease.

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15
Q

What is a case-controlled study?

A

Compares diseased individuals with non-diseased subjects regarding exposure to a factor

This study design is also known as retrospective.

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16
Q

What is a cross-sectional study?

A

Compares two groups based on disease status regarding exposure status

This study design assesses the relationship between exposure and outcome at a single point in time.