Stem cells
Cells that are not specialised and are completed/divided by mitosis repeatedly, a process called proliferation.
Given the right conditions stem cells can differentiate into specialised cells.
Differentiation
The process by which unspecialised cells like stem cells develop special characteristics to suit particular functions.
During differentiation specific genes are activated causing the cells to produce proteins that shape its role in the body.
Specialised cell
A cell that has developed certain characteristics to perform a specific function/task within an organism. Most specialised cells cannot divide.
-Neurons, muscle cells, liver cells, RBCs, WBCs
What are the 3 stages of stem cell differentiation
Step 1: Totipotent stem cells
A type of stem cell that has the potential to become any type of cell that is necessary for embryonic development (embryo and embryonic membranes).
Ex - Zygote
Step 2: Pluripotent stem cells
Stem cells that can develop into any cell type of the body but cannot form tissues such as the placenta.
They are formed from Totipotent Stem cells.
Ex: Inner cell mass of the blastocyst
Ex: Embryonic stem cells
Step 3: Multipotent stem cells
Stem cells that can develop into a limited range of cell types within a specific tissue or organ system.
Arise from pluripotent stem cells after germ layers form.
Examples:
Hematopoietic stem cells → RBCs, WBCs, platelets
Mesenchymal stem cells → bone, cartilage, fat
Adult stem cells in various tissues
4 types of Embryonic membranes