Translation
Occurs when the code for mRNA is read and converted into an amino acid sequence.
Step 1.
After the mRNA has left the nucleus and moved into the cytoplasm… A ribosome binds to a 5’ end of mRNA, it scans along until it finds a particular sequence of bases - AUG (Start codon).
Step 2.
The ribosome allows the tRNA molecule with an anticodon that is complementary to Aug to bind to the mRNA.
Step 3.
This first tRNA molecule will always have the amino acid Methionine attached to it. The ribosome takes hold of this amino acid.
Step 4.
The ribosome then moves on to the next ‘codon’ (series of 3 bases) and allows a complementary tRNA molecule to bind to it.
Step 5.
The ribosome joins the amino acid from this tRNA molecule to the one before it using a peptide bond.
Step 6.
It then repeats steps 4 and 5 until it reaches a ‘stop codon’ at which there are no more amino acids added to the sequence and the protein is complete.
Step 7.
tRNA molecules are released from the mRNA after the amino acid is removed. They are free to pick up a replacement amino acid and be reused.