Pharmacology > Thiazide diuretics > Flashcards

Thiazide diuretics Flashcards

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1
Q

Examples

A
  • Thiazide diuretics: Bendroflumethiazide, hydrochlorothiazide
  • Thiazide-like diuretics: Indapamide, metolazone
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2
Q

Mechanism

A
  • Inhibits Na/Cl symporter in the DCT -> Stop transport out of lumen -> Hyperosmotic lumen -> Diuresis
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3
Q

Indications

A
  • HTN, Oedema
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4
Q

SE

A
  • Hypercholesterolaemia, gout
  • Hypokalaemia, hyponatraemia, hypomagnesaemia
  • Hypercalcaemia, hyperglycaemia

Important: Impotence

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5
Q

CI

A
  • Renal impairment, gout, DM
  • Electrolyte imbalances
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