Abnormality in body function that threatens
health; known etiology
Disease
Signs and symptoms that appear together,
with no known cause
Syndrome
Unknown cause
Idiopathic
Study of the factors that cause disease
Etiology
The objective and subjective
abnormalities associated with disease
Sings and Symptoms
The pattern of a disease’s development
Pathogenesis
The study of occurrence, distribution,
and transmission of diseases in human populations
Epidemiology
Diseases are native to a local region
Endemic
Occur when a disease affects many people at
the same time
Epidemics
Occur when a disease spreads around the
world
Pandemic
What are the 7 mechanisms that lead to disease?
1.Genetic mechanism
2. Infectious mechanism
3. Neoplastic mechanism
4. Traumatic mechanism
5. Metabolic mechanism
6. Inflammatory mechanism
7. Degeneration
What 6 individual variables can lead to disease?
- Genetics
- Age
- Lifestyle
- Stress
- Environmental factors
- Preexisting conditions
What are the 6 types of pathogenic organisms?
- Viruses
- Prion
- Bacteria
- Fungi
- Protozoa
- Pathogenic animals
Pathogenic protein molecules that convert normal proteins into abnormal proteins
PROteinaceous INfectious particle (Prion)
Abnormal cell
growth
Neoplasms
Tumors remain localized
(encapsulated)
Benign
Tumors spread to
surrounding tissues, or metastasize
Malignant
1) Papilloma – on skin surface (i.e. warts)
(2) Adenoma – found in glandular epithelial tissues
(3) Nevus – i.e., moles
Benign, epithelial tumors
(1) Melanoma – skin cancer
(2) Adenocarcinoma – found in glandular epithelial tissues
Carcinomas (malignant epithelial tumors)
(1) Lipoma – adipose tissue
(2) Osteoma- bone tissue
(3) Chondroma- cartilage tissue
Benign, connective tissue tumors
1) Lymphomas- tumor found in lymphatic system
(2) Osteosarcoma- bone tissue tumor
(3) Myeloma- bone marrow tumor
(4) Fibrosarcoma- general term for tumors in fibrous
connective tissues
Sarcomas (malignant connective tissue tumors)
Nerve tissue tumor
Neuroblastoma
Lymphatic tissue tumor
Lymphoma
