Adaptive immunity SDL Flashcards by Hailey Nelson

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Q

What is the complement system?

A

A cascade of plasma proteins (mainly made by the liver) that enhance the immune system’s ability to clear microbes and damaged cells.

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Q

Is the complement system part of the innate or adaptive immune system?

A

innate but can be recruited by antibodies

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Q

What are the three main outcomes of complement activation?

A

Opsonisation (enhanced phagocytosis)

Inflammation & recruitment of immune cells

Direct killing via the membrane attack complex (MAC)

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Q

What are the three complement activation pathways?

A

Classical pathway

Lectin pathway

Alternative pathway

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