Invented the microscope and examined cells
Robert Hooke (1665)
witnessed a live plant cell under the microscope
Anton Van Leeuwenhoek (1647)
proposed a mechanism for photosynthesis and investigated cell respiration in animals
Antoine Lavoisier (1775)
dominated chemistry with the concept of fire; marked onset of physiological chemistry
Phlogiston Theory (177-1783)
Proposed cell theory and fermentation limited to living yeast cells
Theodore Schwann (1836)
showed fermentation depends on the physiological functions of bacteria and living yeast cells
Louis Pasteur (1856)
Protoplasm carries out intracellular processes
1860’s
identified “nuclein” inside the nulcei of human white blood cells
Friedrich Miescher (1869)
prepared zymase, fermented it to glucose, and introduced the concept of an enzyme
Eduard Buchner (1900)
the term “biochemistry” was officially created by german, chemist Carl Neuberg
1903
Discovered the order of nucleotide components and the carbohydrate components of RNA and DNA.
Phoebus Levene (1919)
Discovered the process of citric acid cycle
Hans Krebs (1973)
Suggested that DNA was the genetic material of a cell
Oswald Avery (1994)
Challenged the Leven’s conclusions, discovered that DNA compositions vary among species, and postulated “Chargaff’s Rule”.
Erwin Chargaff (1950)
Cracking of the genetic code, revealing 64 triplets of nucleotides (codons)
1961
Sequenced the genome of a bacteriophage and the DNA of the human mitochondrial genome.
Fred Sanger (1977)
Biochemistry helped the world of science in new research and inventions.
Present Time