CROHNS Flashcards

(71 cards)

1
Q

What type of disease is Crohn’s disease?

A

Inflammatory bowel disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Is Crohn’s disease chronic or acute?

A

Chronic relapsing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which parts of the GI tract can Crohn’s affect?

A

Any part from mouth to anus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Most commonly affected site in Crohn’s?

A

Terminal ileum and colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pattern of inflammation in Crohn’s?

A

Patchy skip lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Depth of inflammation in Crohn’s?

A

Transmural

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Is rectal involvement always present in Crohn’s?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Core bowel symptom of Crohn’s disease?

A

Chronic diarrhoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Is diarrhoea in Crohn’s usually bloody?

A

Usually non-bloody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Abdominal pain location in Crohn’s?

A

Right lower quadrant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Systemic symptom seen in Crohn’s?

A

Weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Another systemic symptom of Crohn’s?

A

Fatigue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fever suggests what in Crohn’s?

A

Active inflammation or infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Perianal feature seen in Crohn’s?

A

Fistulae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Another perianal feature in Crohn’s?

A

Abscesses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Skin tag finding associated with Crohn’s?

A

Perianal skin tags

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Age group commonly affected by Crohn’s?

A

15–30 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Smoking effect on Crohn’s disease?

A

Increases risk and severity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Family history risk factor for Crohn’s?

A

Family history of IBD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Key complication of transmural inflammation in Crohn’s?

A

Fistula formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Another complication of Crohn’s?

A

Strictures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Why do strictures occur in Crohn’s?

A

Fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Nutritional complication of Crohn’s?

A

Malnutrition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Vitamin deficiency common in Crohn’s?

A

Vitamin B12 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Bone complication of Crohn’s?
Osteoporosis
26
Cancer risk increased in Crohn’s?
Colorectal cancer
27
Extra-intestinal systems affected in Crohn’s?
Joints eyes skin liver
28
First-line treatment for mild-moderate Crohn’s?
Oral corticosteroids
29
Steroid commonly used for ileocaecal Crohn’s?
Budesonide
30
Role of aminosalicylates in Crohn’s?
Limited benefit
31
Indication for antibiotics in Crohn’s?
Perianal disease or abscess
32
Antibiotic commonly used in Crohn’s?
Metronidazole
33
Treatment for steroid-dependent Crohn’s?
Azathioprine
34
Alternative immunomodulator for Crohn’s?
Mercaptopurine
35
Biologic used in Crohn’s disease?
Infliximab
36
When are biologics indicated in Crohn’s?
Moderate to severe disease refractory to steroids
37
Role of surgery in Crohn’s?
Not curative
38
Why is surgery not curative in Crohn’s?
Disease recurs at anastomosis
39
Indication for surgery in Crohn’s?
Strictures fistulae or obstruction
40
Maintenance treatment aim in Crohn’s?
Maintain remission
41
Are steroids used for maintenance in Crohn’s?
No
42
Maintenance drugs used in Crohn’s?
Immunomodulators or biologics
43
Analgesic recommended in Crohn’s?
Paracetamol
44
Analgesics to avoid in Crohn’s?
NSAIDs
45
Antidiarrhoeals caution in Crohn’s?
Risk of obstruction
46
Key feature distinguishing Crohn’s from UC?
Transmural skip lesions
47
Another feature distinguishing Crohn’s from UC?
Perianal disease
48
Pattern of bowel involvement in Crohn’s disease?
Patchy skip lesions
49
Is rectal involvement universal in Crohn’s?
No rectal sparing is common
50
Macroscopic mucosal appearance in Crohn’s?
Cobblestone appearance
51
Early mucosal lesion in Crohn’s disease?
Aphthous ulcers
52
Characteristic fat change seen in Crohn’s?
Creeping fat
53
Most commonly affected bowel site in Crohn’s?
Terminal ileum
54
Which vitamin deficiency is common in ileal Crohn’s?
Vitamin B12 deficiency
55
Cause of diarrhoea after ileal disease or resection?
Bile salt malabsorption
56
Drug used for bile salt diarrhoea?
Cholestyramine
57
Smoking advice in Crohn’s disease?
Strongly encourage smoking cessation
58
Effect of smoking on Crohn’s disease?
Worsens disease and increases relapse
59
Is surgery curative in Crohn’s disease?
No
60
Why is surgery not curative in Crohn’s?
Disease recurs at anastomosis
61
Common indication for surgery in Crohn’s?
Strictures fistulae or obstruction
62
Test required before starting azathioprine?
TPMT level
63
Why check TPMT before azathioprine?
Risk of myelosuppression
64
Role of aminosalicylates in Crohn’s?
Less effective than in UC
65
Use of NSAIDs in Crohn’s disease?
Avoid
66
Hallmark feature distinguishing Crohn’s from UC?
Transmural inflammation
67
Another distinguishing feature of Crohn’s?
Perianal disease
68
Management of asymptomatic fistulae in Crohn’s?
Observe and no treatment
69
Antibiotics used for fistulating Crohn’s?
Metronidazole or ciprofloxacin
70
Duration of immunosuppression for fistulating Crohn’s?
At least one year
71
Biologic used if fistulating Crohn’s does not respond?
Infliximab