Top Drawer - syd > Edrophonium > Flashcards

Edrophonium Flashcards

(16 cards)

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1
Q

Brand Names

A

Enlon
Enlon Plus (with atropine)

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2
Q

Broad Class

A

NMBA reversal agent

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3
Q

Pharmacological Class

A

Anticholinesterase

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4
Q

Structural considerations

A

Quaternary amine
Has an ionic bond in it

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5
Q

MOA

A

Same as Neostigmine

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6
Q

Indications

A

Reversal of Nondepolarizers (best at reversing mivacurium)

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7
Q

Dosing (Enlon)

A

0.5-1 mg/kg

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8
Q

Enlon Plus Dosing

A

0.05-0.1 mg/kg

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9
Q

Standard Atropine dosing

A

7-10 mcg/kg (which is the same as)

0.014 mg per 1 mg of edrophonium

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10
Q

CV effects

A

Muscarinic: Profound bradycardia, and hypotension (why atropine is given with it)

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11
Q

Respiratory effects

A

Muscarinic: Bronchospasm, Salivation

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12
Q

CNS effects

A

Miosis

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13
Q

GI effects

A

Increased motility

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14
Q

Onset

A

1-2 mins

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15
Q

Duration

A

˜30 mins (may need to redose)

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16
Q

Excretion

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