do viroids make protein
no
do satellite RNA need a helper virus
yes
do viroids need help
no
what do viroids hijack
the cellular transcription
enzymes that viroids need (3)
RdRp
RNAase
ligase
what are viroids (avsunviroidae) cleaved by
Ribozyme
what does viroid hijack (what enzyme)
DNA dependent RNA polymerase
are viroids self replicating
yes through DNA dependent RNA polymerase
satellite depend on what for replication
helper viruses
3 classes of satellites
- linear RNA - encodes non structural protein
- linear RNA - no protein
- circular (encodes protein)
Aden associated virus structure
single stranded DNA genome with hairpin ends
does Aden associated virus need a helper virus
yes because its a satellite
cap and rep
cap encapsidates the genome
rep cleaves during replication process
Aden viruses encode what kind of protein
structural protein.
elongation of satellite viruses done by what
host DNA dependent DNA polymerase
prions
misfolded proteins
do prions trigger an immune réponse
nop
are prions transmissible
yes
prpSC are resistant to what
protease K degredation
prpSC can touch proc and what
make it misfold
3 m3chnaisms for development of TSE
infectious
inherited
sporadic
smallest known pathogenic agents
viroids, satellite, and prions
disease caused by viroids and satellite are result of
silencing of host gene expression
