adipose or fat cells
Common in some tissues (dermis of skin);
rare in some (cartilage).
mast cells
Common beneath membranes and along small blood vessels.
Important role in inflammation; can release heparin, histamine, and
proteolytic enzymes in response to injury.
macrophages
Phagocytize to provide protection against foreign and injured
cells.
* Fixed: stay in position in connective tissue.
* Wandering: move by amoeboid movement through the connective
tissue
platelets
Fragments of hematopoietic cells involved in clotting.
Undifferentiated mesenchyme (stem cells)
Have potential to differentiate
into adult cell types.
EXTRACELLULAR MATRIX
collagen
one of the Protein fibers of the extracellular matrix
Most common protein in body; strong,
flexible, inelastic.
reticular
one of the Protein fibers of the extracellular matrix
Fill spaces between tissues and organs.
elastic
one of the Protein fibers of the extracellular matrix:
Returns to its original shape after
distension or compression. Contains molecules of protein elastin
Hyaluronic acid
GROUND SUBSTANCE OF THE MATRIX
polysaccharide. Good lubricant. Vitreous humor of eye.
Proteoglycans
GROUND SUBSTANCE OF THE MATRIX
protein and long polysaccharides called
glycosaminoglycans. Protein part attaches to hyaluronic acid.
Trap large amounts of water.
Adhesive molecules
GROUND SUBSTANCE OF THE MATRIX
hold proteoglycan aggregates together.
Chondronectin in cartilage, osteonectin in bone, fibronectin
in fibrous connective tissue.
Embryonic CT
CLASSIFICATION OF CONNECTIVE TISSUE
Mesenchyme.
Mucous CT.
Adult CT
CLASSIFICATION OF CONNECTIVE TISSUE
Connective Tissue Proper.
Loose – fewer fibers, more ground substance; areolar, adipose, reticular
Supporting CT
CLASSIFICATION OF CONNECTIVE TISSUE
* Dense – more fibers, less ground substance; dense regular and irregular
collagenous, dense regular and irregular elastic
* Cartilage – semisolid matrix; hyaline, fibrocartilage, elastic
* Bone – solid matrix; spongy and compact