Function of integumentary system
epidermis
Superficial layer of stratified squamous epithelial issue
reduces water loss
* Avascular; nourished by diffusion from capillaries of the
papillary layer of the dermis.
* Composed of epithelial cells arranged into layers or strata.
* Separated from dermis by basement membrane.
Keratinocytes
epidermal cell type
Kera-nocytes: most cells. Produce keraCn for strength.
Melanocytes:
epidermal cell type
Melanocytes: contribute to skin color. Melanin produced by these cells then transferred to keratinocytes. Same number of melanocytes in all people.
Langerhans cells:
epidermal cell type
part of the immune system
Merkel cells:
epidermal cell type
detect light touch and superficial pressure.
Keratinization:
epidermal cell type
as cells move outward through the layers they fill with keratin, die, and serve as a layer that resists abrasion and forms permeability layer.
name epidermal cell types
Keratinocytes, Melanocytes, Langerhans cells, Merkel cells, Keratinization
Stratum basale (germinativum).
part of Epidermal Strata
* Deepest portion of epidermis and single layer of cuboidal or columnar cells.
* High mitotic activity; keratinocyte stem cells undergo mitosis about every 19 days; one daughter cell remains in the stratum basale to divide again, while the other daughter cell is pushed to the surface and becomes
keratinized.
* Desmosomes hold the keratinocytes together and provide structural strength.
* It takes 40 to 56 days to move from the stratum basale to the surface and
be sloughed off.
Stratum spinosum.
part of Epidermal Strata
* Eight to ten layers of many-sided cells that flatten as they are pushed upward.
* Contain new desmosomes, lipid-filled lamellar bodies, and additional keratin fibers.
Stratum granulosum
part of Epidermal strata
* Two to five layers of flattened, diamond-shaped cells.
* Contains protein granules of keratohyalin that accumulate in the cytoplasm.
* Lamellar bodies move to the plasma membrane and release their lipid contents
into the extracellular space.
*the keratin fibers and keratohyalin granules do not degenerate.
Stratum lucidum.
part of Epidermal strata
* Thin, clear zone of dead keratinocytes with indistinct boundaries.
* Found only in palms and soles.
Stratum corneum.