1- B. The ability to recognize the form and texture of an unseen familiar object is called stereognosis. This is an important function of the dorsal column-medial lemniscus system.
2- C. The corticospinal tracts arise from upper motor neurons (UMNs) found in lamina V of the cerebral cortex. They descend through the posterior limb of the internal capsule, the middle third of the crus cerebri (basis pedunculi) of the midbrain, and the base of the pons and constitute the medullary pyramids. Ninety percent of the corticospinal fibers decussate in the caudal medulla as the pyramidal decussation.
3- D. Destruction of ventral horn motor neurons results in a lower motor neuron (LMN) lesion and is characterized by flaccid paralysis, muscle atrophy (loss of muscle bulk), and areflexia (loss of muscle stretch and superficial abdominal reflexes). The Babinski sign is not seen in LMN disease.
4- D. The dorsal spinocerebellar tract is an uncrossed tract.
5- A. The corticospinal (pyramidal) tracts receive contributions from the premotor (area 6), motor (area 4), and the sensory or somatesthetic (areas 3, 1, and 2) cortices. They receive approximately one-third of their axons from each of these cortical areas. The paracentral lobule represents a continuation of the motor and somatesthetic cortices onto the medial aspect of the hemisphere. The prefrontal cortex lies rostral to the premotor cortex.
6- G. The vestibulospinal tract arises from the giant cells of Deiters found in the ipsilateral lateral vestibular nucleus of the pons. The vestibulospinal tract facilitates extensor muscle tone.
7- A. The cuneocerebellar tract is the upper extremity equivalent of the dorsal spinocerebellar tract, which arises from the cells of the Clarke column. The cuneocerebellar tract arises from cells of the accessory cuneate nucleus, a homolog of the nucleus of Clarke.
8- E. The lateral spinothalamic tract conveys nociceptive input from the contralateral side of the body.
9- D. The lateral corticospinal tract contains axons from the giant cells of Betz. The giant pyramidal cells of Betz are found in the precentral gyrus and in the anterior paracentral lobule.
10- F. The dorsolateral tract of Lissauer contains ipsilateral pain fibers that have their second- order neurons in the dorsal horn.
11- B. The dorsal spinocerebellar tract projects unconscious proprioceptive information [muscle spindles and Golgi tendon organs (GTOs)] to the cerebellum via the inferior cerebellar peduncle.
12- C. The lateral spinothalamic tract lies between the ventral spinocerebellar tract and the ventral horn. It mediates pain and temperature sensation.
13- E. The lateral corticospinal tract has its cells of origin in the premotor, motor, and sensory cortices. The precentral gyrus and the anterior paracentral lobule are motor cortices and contain the motor homunculus. It gives rise to one-third of the fibers of the corticospinal (pyramidal) tract.
14- F. The fasciculus cuneatus mediates two-point tactile discrimination from the hand.
15- E. The corticospinal (pyramidal) tracts are not fully myelinated until the end of the second year. For this reason, the Babinski sign may be elicited in young children.
16- E. Transection of the lateral corticospinal tract results in spastic paresis [exaggerated muscle stretch reflexes (MSRs) and clonus].
17- D. The vestibulospinal (lateral) tract, found ventral to the ventral horn, plays a role in regulating extensor tone.
18- A. The fasciculus gracilis transmits vibratory sensation (pallesthesia) from the lower extremities.