Diazepam

Question 1

Pharmacology and presentation of Diazepam?

Answer 1

5mg Tablet

A benzodiazepine that potentiates GABAA (Inhibitory neurotransmitter) resulting in anxiolytic/sedative effects

Question 2

Indicators of Diazepam?

Answer 2

• Acute behavioural disturbance (SAT Score >0).

Question 3

Contraindications of Diazepam?

Answer 3

• Hypersensitivity to benzodiazepines
• Myasthenia gravis

Question 4

Cautions of Diazepam?

(CHURR)

Answer 4

• CNS Depression or ingestion of depressing agents
• Hypotension
• Use in elderly/children/frail
• Renal/hepatic function impairment
• Respiratory depression

Question 5

Side Effects of Diazepam?

Answer 5

• Extrapyramidal reactions (parkinsonian like symptoms, acute dystonia and akathisia)

Question 6

Dosing Regimes of Diazepam?

Answer 6

.

Question 7

Onset and duration of Diazepam?

Answer 7

• Onset = 15-60 minutes
• Peak = 30-90 minutes
• Duration = 12 hours