Prochlorperazine

Question 1

Pharmacology and presentation of Prochlorperazine?

Answer 1

12.5mg/1ml Ampoule

Prochlorperazine is an antiemetic and antipsychotic drug that acts on several central neurotransmitter systems.

Question 2

Indicators of Prochlorperazine?

Answer 2

• Treatment or prophylaxis of nausea/vomiting in: motion sickness, penetrating eye injury and aeromedical evacuation
• Vertigo or nausea or vomiting associated with migraine, labyrinthitis or Meniere’s syndrome
• Know allergy or contraindication to Metoclopramide administration

Question 3

Contraindications of Prochlorperazine?

Answer 3

• Hypersensitivity
• Circulatory collapse
• CNS depression
• Children <2 years

Question 4

Cautions of Prochlorperazine?

Answer 4

• Hypotension
• Epilepsy
• Patient on anti-depressants or affected by alcohol.

Question 5

Side Effects of Prochlorperazine?

(DR BETH)

Answer 5

• Drowsiness
• Blurred vision
• Hypotension
• Tachycardia
• Skin rash
• Extrapyramidal reaction (Dystonia)

Question 6

Dosing Regimes of Prochlorperazine?

Answer 6

.

Question 7

Onset and duration of Prochlorperazine?

Answer 7

• Onset = 20 minutes
• Duration = 6 hours