Hema Flashcards

(10 cards)

1
Q

Hans algorithm
Germinal center

A

CD10+
or
CD10- BCL6+ MUM1-

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2
Q

PNH screening

A

sucrose test

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3
Q

PNH confirmation

A

flow cy (CD55)

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4
Q

Hb Barts

A

four gamma-globin chains

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5
Q

function of ADAMTS13

A

cuts large vWF strands to prevent plt clumping

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6
Q

B-ALL translocation assoc with good prognosis >90% cure rate

A

t (12;21)/ ETV6-RUNX1

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7
Q

NGS required tumor content and tumor cells

A

> 10%
1000 tumor cells

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8
Q

LCH
solitary bone
multiple bone
multiple organ

A

eos granuloma
Hand-Schuller-Christian - exopthalmos, DI
Letterer-Siwe - fatal, skin rash

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9
Q

lipid-storing histiocytosis of non-langerhans type

A

Erdheim-Chester disease

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10
Q

TS (transferrin saturation) in IDA

A

Ratio of serum iron to IBC (iron binding capacity)

Normal: 1:3
IDA: 1:5 or lower

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