IS

Question 1

CGD diagnosis in F test
in flow cy
defect

Answer 1

<10% F+ cells
dihydrorhodamine 123
NADPH oxidase def.

Question 2

RBC phenotype in CGD

Answer 2

McLeod (absence of Kell)

Question 3

Duncan disease

Answer 3

due to EBV
inverted CD4:CD8
SH2D1A gene - SAP

Question 4

Chediak-Higashi defect and gene

Answer 4

degranulation (large granules)
LYSY/CHS1 - lysosomal trafficking regulator

Question 5

NK cell function assessed by

Answer 5

chromium release assay

Question 6

PBC antibody

Answer 6

AMA

Question 7

autoimmune hepa antibody

Answer 7

anti-smooth muscle ab
anti-liver kidney microsomal

Question 8

MPO-ANCA
(p-ANCA)

Answer 8

PSC, UC
microscopic polyangiitis
PAN
Churg-Strauss

Question 9

polyarteritis nodosa assoc

Answer 9

Hep B

Question 10

PR3-ANCA
(c-ANCA)

Answer 10

Wegener (granulomatosis w/ polyangiitis)

Question 11

intradermal injection

Answer 11

5-10 mm wheal

Question 12

skin-prick method

Answer 12

3mm

Question 13

PBC criteria

Answer 13

2/3
AMA more or equal to 1:40
ALP more than or equal to 1.5x upper limit >2yrs
compatible liver histology

Question 14

Insulin autoantibody in type 1 DM not used for

Answer 14

patients treated with insulin for more than 14 days

Question 15

MS diagnosis

Answer 15

glucose normal
WBC <10 monos/uL
protein <60 mg/dl
MBP >4 ng/ml

no autoabs

Question 16

Type 1 DM antibodies and method

Answer 16

Islet cell cyto autoantibody - indirect immunoassay

Question 17

dx of allergic disease in IgE

Answer 17

+1 SD

Question 18

basophil activation assay

Answer 18

CD63