mutation in blue nevus
GNAQ
mutation in pigmented nevus
BRAF
bridging of adjacent nests along rete ridges
dysplastic nevus
kamino bodies
spitz nevus
melanoma mutations
CDKN2A, BAP1
desmoplastic melanoma IHC
(+) S100
(-) HMB45, Melan A
multiple trichilimemmomas
Cowden syndrome
Muir Torre syndrome, mutation
sebaceous and visceral tumor
AD form of HNPCC
MSH2
mutation in seb ker
FGFR3
leser-trelat sign
GI AdenoCA TGF-a stimulates keratinocytes
Birt-Hogg-Dube syndrome
benign skin tumors, lung cyst, kidney lesions
Gardner syndrome
AD form of FAP, EICs
intraepidermal porom
hidroacanthoma simplex
eccrine acrospiroma
hidradenoma
hidradenoma IHCs
(+) S100, keratin vs. glomus tumor
tadpole or comma like
syringoma
cutaneous mixed timor
chondroid syringoma
multiple cylindromas syndrome? mutation?
Brooke-Spiegler, CYLD in ch 16 tumor supp inactivation
jigsaw puzzle
cyclindroma
blue balls in dermis, intermingled lymphs, painful
spiradenoma
sebaceoma va seboceous adenoma
adenoma - more sebocytes than seboblasts
trichiepithelioma vs BCCA
(+) CK20
Brooke-Spiegler
pilomatricoma other name, mutation
calcified epithelioma of Malherbe
CTNNB1
BCCA IHC vs SCCA
(+) Ber-EP4, CD10
