What is the concept of clearance?
Determines how much of a substance can be cleared from the body by the kidneys per given unit of time
How is clearance rate via glomerular filtration rate (GFR) estimated?
By comparine blood creatinine to urine creatinine
How to interpret clearance rate via GFR
BUN =
Blood urea nitrogen
What is BUN?
Reflects glomerular filtration and urineurine-concentrating capacity
Blood and urea
Urea is filtered in glomerulus, so it shouldn’t be present in blood
When will BUN levels rise?
- dehydration and renal failure
Urinalysis evaluates:
Ureters
Bladder muscle
- lined with transitional epithelium
Urethra
From inferior bladder to outside body
Internal urinary or internal urethral sphincter
Bladder junction controlled by ANS
External urinary or external urethral sphincter
Voluntary control of urination
prostate gland
Main function of prostate gland
secrete prostate fluid, which is a component of semen