Study Guide Leftovers 4

Question 1

Chemotherapy agents: seed and soil tx rationale

Answer 1

• Limit cell proliferation by killing or attenuating growth (SEED)
• Make environment inhospitable for cancer cells (SOIL)

Question 2

Difference in chemo agents and radiation (types of cancer treated)

Answer 2

• chemo useful in widespread or metastatic disease

- radiation is more useful for localized lesions

Question 3

Almost all chemo agents kill cancer cells by affecting

Answer 3

DNA synthesis or function

• each drug varies in how this occurs

Question 4

Why are combination therapies often used with chemo drugs?

Answer 4

some drugs work better during different cell cycles

Question 5

Chemotherapy agents: given in what forms?

Answer 5

• orally
• subcutaneously
• intravenously
• intracavitarily
• intrathecally
• etc

Question 6

Exercise with an oncology pt: How do you monitor response to tx?

Answer 6

• RPE and vitals (not always reliable)
• exertional dyspnea
• SOB
• dizziness and stuff
• lab values if available

Question 7

What are common cancer sx that are masquerading as MSK conditions?

Answer 7

• proximal muscle weakness

- peripheral neuropathy