What findings would you find in arterial diseases regarding the following:
Why is PAD worse at night sometimes? What would this indicate?
When you’re upright during the day, gravity helps pull blood down into your legs, so even with narrowed arteries, some flow still makes it through.
At night, lying flat removes that help — your legs are at heart level, so the already low perfusion pressure in PAD drops even more.
muscle tissues hurting at rest because of low oxygen supply
What would indicate mild PAD?
What would indicate severe PAD?
mild: only claudication (pain on walking) - stenosed arteries cant dilate enough to meet the higher demand
severe: rest pain, especially at night = red flag for critical limb ischaemia
What is the difference in the images?
left: venous ulcer
- varicose veins, previous DVT, obesity
- usually between lower calf and medial malleolus
- shallow and flat margins, mod to heavy exudate, slough at base with granulation tissue
- treated with compression therapy, leg elevation, surgical management
right: arterial ulcer
- diabetes, htn, smoking, previous vascular disease
- pressure points, toes and feet, lateral malleolus and tibial areas
- punched out and deep, irregular shape, unhealthy wound bed, necrotic tissue, minimal exudate unless infected
- treated with revascularisation, anti-platelet medication, manage risk factors
A 58-year-old smoker develops calf pain after walking 200 m, which resolves after resting for 5 minutes. On exam, dorsalis pedis pulse is weak.
What is the most likely diagnosis and pathophysiology?
PAD due to atherosclerotic narrowing of leg arteries, causing reduced oxygen supply during exercise → intermittent claudication.
A 70-year-old man with atrial fibrillation presents with sudden-onset severe left leg pain, pallor, and absent distal pulses.
What is the most likely cause?
Arterial embolism (often from left atrium in AF) causing acute arterial occlusion — “6 P’s”: pain, pallor, pulselessness, paresthesia, paralysis, poikilothermia
A 64-year-old woman with PAD has a painful ulcer on her lateral malleolus. The ulcer has a “punched-out” edge, pale base, and minimal exudate.
What type of ulcer is this and why is it painful?
arterial ulcer — due to ischaemia; pain worsens with elevation because gravity no longer assists perfusion
A 55-year-old man with varicose veins complains of ankle swelling and dull aching after standing all day. Brownish skin changes are seen above the medial malleolus.
What is the underlying mechanism?
incompetent venous valves cause venous hypertension → capillary leakage → hemosiderin deposition and oedema
A 62-year-old woman has a shallow, exudative ulcer above the medial malleolus with surrounding hyperpigmentation.
What is the most likely diagnosis and key difference from arterial ulcer?
venous ulcer - occurs with venous hypertension, usually less painful, with more exudate and irregular edges, compared to the dry, punched-out arterial ulcer
Which bedside test assesses ulnar artery patency before radial artery cannulation?
modified allen test
Which test distinguishes superficial from deep venous valve incompetence?
trendelenburg
Which test involves elevating the leg to 45° to assess for pallor and reactive hyperaemia?
buerger’s test