If SSRI isnt working ?
Try another SSRI or SNRI for GAD
TCAs side effects
Overflow incontinence
Drowsy, dry mouth, blurred vision, constipation, urinary retention. lengthened QT
Serotonin syndrome
MAOIs, SSRIs
ST johns wort and tramadol
Ecstasy and amphetamines
Hypreflexia, hyperthermia, myoclonus, sweating
Confusion
—> IV fluids and benzodiazepines
NMS
Hours- days
Pyrexia, muscle rigidity, HTN, tachycardia , tachypnoea, Normal pupils
Raised CK, AKI and leukocytosis
IV fluids, stop antipsychotic, dantrolene
Alcohol withdrawal
Decreased GABA and increased NMDA
0-12 hours - tremor
36 hours - seizures
72 hours - delirium tremens (hallucinations)
Give chlordiazepoxide OR in liver cirrhosis needs to be lorazepam
Serotonin discontinuation symptoms
Increased mood change, restlessness, difficulty sleeping, unsteadiness, sweating, GI symptoms e.g. pain, cramping, diarrhoea, vomiting, paraesthesia
Antipsychotics caution side effects in elderly
Increased risk of stroke and VTE
What happens if clozapine doses are missed for 48 hours
Restart dose again slowly
Schizophrenia first rank symptoms
Thought insertion and withdrawal and broastcarsting
Delusional
Hallucination
Body being controlled by outside influence
T1 vs T2
t2 - hypomania
SSRI in 3rd trimester
Pulmonary HTN risk in newborn
Oculogyric crisis
Dystonic reaction
Give IM procyclidine
Tetrabenzine
Tardive dyskinesia antidote
Anorexia
G and Cs raised
GH, Glucose, salivary glands, cortisol, cholesterol, carrotinaemia
Personality disorders clusters
A - Weird eg paranoid, schizoid, schizotypal
B - Emotional or impulsive e.g. antisocial, borderline, narcissistic
C- Anxious (wobbly), Obsessive compulsive, avoidant, dependent
Personality disorders treatment
DBT
Depression treatment
Guided self help first line if not sever e
If over 16- give them CBT and SSRI
Anorexia treatment
CBT- ED for adults
Anorexia family therapy for children
Histrionic
Attention seeking
Section 2, section 3, section 4, section 5(2), section 5(4)
2- 28 days
3- 6 months
4- 72 hours
5 (2)- 72 hours
5 (4) - 6 hours ( nurse)
135 and 136
135- court order for police to break in
136- take the to a place of safety
Bulimia
Hypocholeramic, hypokalaemia alkalosis
1x a week for 3 weeks
Bulimia self help
if ineffective after 4 weeks —-> CBT ED
MAOIs hypertensive reactions
With tyramine containing foods e..g cheese, marmite and broad beans
Somatisation
Multiple physical symptoms present for 2 years
Patient refuses to accept reassurance or negative test results