Nephrotic
HSP, minimal change, FSGS
Renal cell carcinoma
Clear cell
Smoking risk factor
Haematuria, loin pain, pyrexia of an unknown location
ADENOCARCINOMA
Left sided varicocele
Cholestasis/ hepatosplenomegaly
USS CT kidneys and CT TAP- cannonball
Total nephrectomy
If <7cm –> partial nephrectomy
Bladder cancer
TCC-smoking, aromatic amines
SCC- schistomatosis
Most likely TCC
TURBT if no muscle invasion
Radial cystocetomy if invasive
Testicular cancers
Infertility is risk factor
teratomas is 25 years and seminomas is 35 years
Painless lump, hydrocele, non tender, hard irregular
Gynaecomastia - germ cell and leydig cell
SCtoral USS, HCG high in seminaomas
LDH high in germ cell
Orchidectomy
Prostate cancer
Risk factors - age, obesity, anabolic steroids, tall
LUTS, haematuria, ED
PSA, PR exam, multi parametric MRI
Prastectomy, radiotherapy.
Metastatic - hormonal e..g goserelin, cover with anti androgen
PSA rules
Wait 6 weeks post treatment of prostatitis/ UTI
Ejection and exercise - not for 48 hours
Side effects of radical prostatectomy and radiotherapy
Radiotherapy - proctitis , bladder colon rectal cancer
Radical prosatectomy - erectile dysfunction
Epididmyorchitis
Painful, discharge, unilateral
E coli or chlymadia/ gonorrhoea or mumps
USS check for torsion
NAAT for young, MC+S for old
IV ABX if acutely unwell
Quinolone for UTIs and ofloxacin for e coli
Epididymal cysts
Simple cysts separate to the body of the testicle
Non painful, above and below
USS
PCKD, CF
Varicocele
Asymptomatic, may be associated with infertility
L>R, bag of worms
USS
Hydrocele
Non painful, fluctuant, transilluminates, soft
Must do an USS
Could be testicular cancer
Inguinal hernia
Cant get above it
High chance of strangulation
Testicular torsion
Severe and sudden
Cremasteric reflex lost
Prehn’s sign ( elevation doesn’t ease the pain)
urgent surgical exploration- fix both
Paraphimosis
Not replacing a retracted foreskin
Commonly seen post catheterisation
Apply pressure
Dorsal slit if the last resort
Phimosis
Foreskin tight and can’t be retracted
Normal in babys
Adults - STIs, eczema, lichen sclerosis, balantitis
Membranous glomerulonephritis
Malignancy
Nephrotic or haematuria
Cycloglobinurea, hep B or C
Good pasture
Anti GBM antibodies
Haemopytsis
Haematuria
Pulmonary haemorrhage
High transfer factor, IgG deposits
Plasmapheresis, cyclosphosamide, steroids
Alports
Children, microscopic haematuria bilateral sensineural deafness, sight reduced
Granulomatosis with polyangitis (Wegner’s)
Renal failure
Epistaxis/ haemopysis
cANCA
Sinusitis, vasculitis, dyspnoea
Eosinophilic granulomatosis with polyangitis (Churg- Strauss)
Asthma
pANCA
eosinophilia
Sinusitis, vasculitis , dyspnoea
IgA
1-2 days post URTI
Nephrotic syndrome
Steroids
Increased risk of VTE due to loss of antithrombin III –> VTE prophylaxis
post strep
1-2 weeks post URTI
Aspirin overdose
IV sodium bicarbonate
Raised anion gap metabolic acidosis, nauseam vomiting, tinnitus