3.14 Ch. 12.3

Question 1

What does MG damage?

Answer 1

ACh receptors at the NMJ

Question 2

What happens during MG?

Answer 2

repeated use of muscle leads to increasing weakness

Question 3

What does botulism interfere with?

Answer 3

release of ACh from motor axon

Question 4

What happens with botulism?

Answer 4

• produces acute, progressive weakness
• loss of stretch reflexes
• sensation remains intact

Question 5

myopathy

Answer 5

disorder intrinsic to muscles

Question 6

myopathy: sensation and autonomic function

Answer 6

• sensation intact
• autonomics intact

*because nervous system is not affected by myopathy

Question 7

Later stages of myopaty

Answer 7

Coordination, muscle tone, and reflexes are unaffected until muscle atrophy becomes so severe that muscle activity cannot be elicited.

Question 8

What are the benefits of using electrodiagnostic studies?

Answer 8

reveals pathologic location and are often diagnostic

Question 9

nerve conduction studies can be used to differentiate among these:

Answer 9

• primarily myelinopathy and axonopathy processes
• UMN and LMN paresis
• mononeuropathy and polyneuropathy
• local conduction block and Wallerian degeneration

Question 10

3 clinical signs of peripheral neuropathy are revealed in:

Answer 10

• ≥ 50 yo
• presence of 2-3 s/s

*correlate with highly electrodiagnostic evidence of peripheral neuropathy

Question 11

3 clinical signs of peripheral neuropathy

Answer 11

• Absence of ankle jerk reflex despite facilitation
• Impaired vibration
• Impaired position sense of the great toe

Question 12

evaluation of polyneuropathy: What increases along with severity of neuropathy?

Answer 12

reports of pins and needles sensations

Question 13

evaluation of polyneuropathy: signs of damage result from

Answer 13

hypoactivity or hyperactivity of neurons

Question 14

Important thing when evaluating for polyneuropathy

Answer 14

distinction between PNS and CNS dysfunction is vital**

Question 15

What guides treatment decisions for polyneuropathy?

Answer 15

• sensory
• MMT
• EMG/NCV

Question 16

Why is education so important with polyneuropathy?

Answer 16

prevent complications from the damage caused by

• lack of sensation
• disuse
• overuse

Question 17

treatment for peripheral polyneuropathy (education)

Answer 17

• visually inspect areas daily for wounds

- proper foot care

Question 18

treatment: interventions for edema

Answer 18

• elevation of limb
• compression bandaging
• e-stim

Question 19

treatment of polyneuropathy: contractures prevented by

Answer 19

• prolonged stretching

- daily activities

Question 20

endurance exercise after peripheral nerve crush injury

Answer 20

enhances sensory and motor recovery

Question 21

resistance exercise after peripheral nerve crush injury

Answer 21

may delay functional recovery (or combo of resistance and endurance)

Question 22

treatment for polyneuropathy: exercise

Answer 22

emphasize gradual strengthening and functional use of individual muscles and groups

Question 23

orthoses for the treatment of polyneuropathies are used to

Answer 23

stabilize WB joints

Question 24

orthoses prevent:

Answer 24

• sprains and strains
• drooping of forefoot during gait
• deformities from paresis, paralysis, and lack of sensation

Question 25

drooping of forefoot during gait caused by

Answer 25

paresis or paralysis of tibialis anterior