Where does most acid come from?
CO2 production, excreted through lungs
what are non-volatile acids
Acidic byproducts that cannot be removed from lungs, sometimes kidneys or other ways.
What are protons buffered by?
blood, not normally filtered
What must happen to bicarbonate to avoid acidification
reabsorbification - 100% effective
how does bicarbonate effect pH
binds H+ n plasma to raise pH (alkalosis)
Under normal vs Alkaline conditions
Normal ~ all bicarbonate reabsorbed
Alkaline ~ some biocarbonate excreted