Kidneys Flashcards

(33 cards)

1
Q

What is water movement faciitated by

A

channels, osmosis, filtration, and absorption

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2
Q

U/P =1

A

isoOsmotic

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3
Q

U/P > 1

A

Urine is hyperOsmotic ~ Urine releases solutes and solute content is decreased in plasma

Dehydration

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4
Q

U/P < 1

A

Urine is hypoOsmotic ~ Urine excretes water and solute content is released into plasma

Over hydration

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5
Q

3 reasons animals need water

A

respiratory water loss
fecal loss
urinary loss

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6
Q

what 3 things does the kidney produce

A

filtrate, ultrafiltrate, primary urine

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7
Q

what is the output from kidneys after processing

A

definitive Urine

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8
Q

3 functions of kidney

A

Filtration - rate is regulated
Absorption - filtered components can be re-absorbed
Secretion - Components that arent filtered are then added to filtration

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9
Q

What collects urine output?

A

Renal Pelvis, then drains to ureter which travels to bladder

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10
Q

Where are nephrons located?

A

Cortex and Medulla

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11
Q

What are nephrons composed of

A

1) Bowman’s capsule
2) Proximal Tubules
3) Loop of Henle
4) Distal Tubules
5) end at collecting duct

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12
Q

2 capillary networks of Nephrons

A

Glomerular capillaries - Bowman’s capsule
Pertibular Capillaries - Loop of Henle

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13
Q

Blood pathway in Kidney

A

1) Afferent Ateriole

2) Glomerular Capillaries (filtration step takes to bowman’s capsule)

3) Efferent Arteriole

4) Pertibular Capillaries (secretion can take to loop of Henle and absorption can take from Loop of henle to here)

5) Venules

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14
Q

Structure and Function of glomerular filtration

A

Nephrons enclose around the Glomerular capillaries.

Filtration is extremely fast here compared to other capillaries, this is due to highly porous nature.

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15
Q

Urine pathway in Kidneys

A

Glomerular Capillaries

Bowman’s Capsule

Proximal Tubule

Loop of Henle

Distal Tubule

Collecting Duct

Ureter

Bladder

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16
Q

What drives glomerular filtration rate?

A

Hydrostatic pressure drives blood into capsule, Osomotic pressure and hydrostatic pressure within the capsule can resist this movement

17
Q

How can GFR be regulated?

A

contraction and dilation of arterioles to affect pressure

18
Q

What is the dominant activity to modify filtrate

19
Q

What is the fate of filtered solutes?

A

majority are re absorbed

Glucose - 100%
Na+ and H2O nearly completely absorbed

Some are secreted into tubules like waste

20
Q

how does length of loop of henle affect urine concentration

A

longer makes higher conc urine

21
Q

Loop of henle function

A

Creates the osmotic gradient in the medulla that allows the kidney to make hyperosmotic (concentrated) urine when you need to save water.

22
Q

when is ADH secreted by posterior pituitary

A

High plasma osmolarity or low plasma volume

23
Q

what does ADH do

A

tell the kidney to absorb more water into the blood

24
Q

Descending Limb in loop of henle function

A

Permeable to water

NOT permeable to solutes

Water leaves → filtrate becomes more concentrated as it moves downward

Think: “Water OUT.”

25
Ascending Limb
Impermeable to water Actively pumps out Na⁺, K⁺, Cl⁻ Filtrate becomes more dilute as it rises Think: “Salt OUT.
26
what does the Atrial natriuertic peptide do in kidney regulation
inhibit sodium reabsorption and reduce fluid vol.
27
Medullary thickness is a measure of what
length of the loops of henle
28
What does the single effect do
ensures filtrate leaves loop of henle more dilute than plasma
29
What does ANP do
reduce fluid volume and blood pressure
30
How does ADH presence affect osmolarity between filtrate and interstitial fluid at the collecting duct.
becomes osmotic - generates hyper osmotic urine
31
What does aldosterone do
increase fluid volume and blood pressure
32
Renin-Angiotensin system
Juxtaglomerular cells secrete renin in response to low BP (low sodium reabsorption) and low osmolarity.
33
What does Renin do
Cleaves angiotensin which ultimately increases volume and pressure.