Catabolic Pathways
Metabolic reactions that break down complex molecules (like sugar) into simpler ones, releasing energy to make ATP
Aerobic Respiration
Cellular respiration that requires oxygen; produces the most ATP (about 30-32 per glucose)
Anaerobic Respiration
Respiration that occurs without oxygen; uses the other electron acceptors instead of O2 and makes less ATP
Fermentation
A type of anaerobic process that allows glycolysis to continue by regenerating NAD+; produces little ATP (only from glycolysis)
Lactic Acid Fermentation
Converts pyruvate –> lactic acid (used by muscles, bacteria)
Alcohol Fermentation
Converts pyruvate –> ethanol + Co2 (used by yeast)
Redox
Reactions involving the transfer of electrons
Oxidation
Loss of electrons
Reduction
Gain of electrons
Reducing agent
the molecule that loses electrons (is oxidized)
Oxidizing agent
the molecule that gains electrons (is reduced)
Cellular Respiration
The overall process cells use to breakdown glucose and make ATP.
NAD+
Empty electron carrier (taxi without passengers)
NADH
Full electron carrier (has picked up electrons and H+
Glycolysis
First step of respiration, splits glucose into 2 pyruvates, producing 2 ATP and 2 NADH, Occurs in the cytoplasm and does not require oxygen
Pyruvate
End product of glycolysis; converted to Acetyl-CoA before entering the Krebs cycle
Krebs cycle
Aerobic process that breaks down Acetyl-COa to produce 6NADH, 2FADH2, and 2 ATP
Electron transport chain (ETC)
Series of proteins in the inner mitochondrial membrane that use electrons from NADH/FADH2 to create a proton (H+) gradient)
Oxidative Phosphorylation
The final stage of cellular respiration (ETC+ chemiosmosis); produces most of the ATP.
Substrate-Level Phosphorylation
Direct formation of ATP when an enzyme transfer a phosphate group from a substrate to ADP (happens in glycolysis and Krebs)
Acetyl-CoA
Two carbon molecule formed from pyruvate; enters the Krebs cycle
Chemiosmosis
Movement of H+ ions across the inner mitochondrial membrane through ATP synthase to generate ATP
ATP Synthase
Enzyme that uses the proton gradient to make ATP from ADP + Pi
Proton-Motive Force
The electrochemical gradient of H+ across the membrane that drives ATP synthesis