Viruses
Infectious particle made of genetic material (DNA or RNA) enclosed in a protein coat. Non-living, can only reproduce inside a host cell
Capsids
The protein shell that encloses a virus’s genetic material
Capsomeres
The protein subunits that make up the capsid
Helical/Icosahedral Viruses
Helical - Rod-shaped viruses
Icosahedral - Spherical viruses with 20-sided symmetry
Envelope
A lipid membrane surrounding some viruses, derived from the host cell’s membrane; helps the virus enter new cells.
Obligate Intracellular Parasites
Viruses must enter a living host cell to replicate and carry out functions; they cannot reproduce independently
Bacteriophages
Viruses that infect and destroy bacteria; have a complex shape with a head, tail, and fibers
Lytic Cycle
The phage infects the host, replicates its DNA and causes the host cell to burst (lyse), release new viruses, results in the immediate destruction of the host cell
Lysogenic Cycle
The viral DNA integrates into the host’s genome and remains dormant for a time, the host cell continues to divide, passing on the viral DNA until it eventually enters the lytic phase
Virulent Phage
A phage that reproduces only by the lytic cycle, always killing the host cell
Restriction enzyme
bacterial enzymes thart cut up foreign DNA (like viral DNA) as a defense mechanism
Temperature Phage
a phage that can alternate between the lytic and lysogenic cycles depending on conditions
Prophage
Viral DNA that has been integrated into the bacterial host’s chromosome during the lysogenic cycle
Provirus
Viral DNA that is integrated into a eukaryotic host’s genome and remains there permanently
Retrovirus
A virus that contains RNA as its genetic material and uses reverse transpiction to make DNA
Reverse transcriptase
The enzyme used by retrovirus to convert RNA into DNA, which is inserted int the host’s genome
Pandemic
A global outbreak of an infectious disease that spreads across countries and continents
Coronavirus
A family of enveloped RNA viruses that cause respiratory illnesses; includes the virus responsibe for COVID-19
SARS-CoV-2
The specific corona virus that causes COVID-19; transmitted through airborne droplets
Horizontal Transmission
Virus spreads from one cell or organism to another
Vertical Transmission
Viruses passes from parent to offspring
Prions
Infectious, misfolded proteins that cause degenerative brain diseases (e.g. mad cow disease); contain no nucleic acids
Vaccines
Preparations that stimulate the immune system to recognize and fight a specific virus if exposed later. They train the body to destroy pathogens before infections takes hold.