Hemostasis

Question 1

Hemostasis:

Answer 1

Mechanism that leads to cessation of bleeding from blood vessels

Question 2

Blood coagulation

Answer 2

Process by which a blood clot is formed, which involves the
participation of activated coagulation factors and co-factors

Question 3

Platelet or thrombocyte:

Answer 3

Cellular fragment of a megakaryocyte that participates in the
first hemostasis step

Question 4

Platelet degranulation

Answer 4

Is a characteristic response of activated platelets in which they
release the content of their secretory granules onto the injured site.

Question 5

Fibrin:

Answer 5

Is the active form of factor I; it is a sticky, threadlike protein that “glues” together
the cells and clotting factors in a blood clot

Question 6

Thrombopoietin:

Answer 6

A liver protein that is the primary regulator of megakaryocyte
development and platelet production

Question 7

Zymogen:

Answer 7

An inactive protein converted to an active enzyme when acted upon by
another enzyme

Question 8

Thrombocytopenia

Answer 8

This is a condition where the animal has a low blood platelet
concentration.

Question 9

Petechiae:

Answer 9

These are pinpoint, round red spots that form in the skin or mucosa. They
are caused by bleeding of small vessels frequently related to thrombocytopenia.

Question 10

Ecchymosis:

Answer 10

These are flat blueish or purple patches measuring half an inch or more
in diameter in the skin or mucosas

Question 11

Fibrinolysis:

Answer 11

is the enzymatic breakdown of the fibrin threads holding the blood clot
together. It is also known as thrombolysis.

Question 12

Vasospasm

Answer 12

Sudden reduction of the blood vessel diameter due to contraction of the
smooth muscles.

Question 13

Hemophilia

Answer 13

Is an inherited blood disorder characterized by inefficient blood clotting. It
is caused by mutations of genes responsible for making blood coagulation factors.