Immunodiagnostics

Question 1

Agglutination

Answer 1

particles (such as red blood cells or bacteria or latex beads) suspended in a liquid collect into clumps in response to an antigen or antibody. COOMBS TEST

Question 2

Cell culture

Answer 2

removal of cells from an animal and their subsequent growth in a favorable artificial environment (in vitro).

Question 3

Cell culture examples

Answer 3

Primary Cell culture and Secondary Cell cultures (genetic change from primary).

Question 4

Cell line

Answer 4

population of cells that can be maintained in
culture for an extended period of time, retaining stability of certain phenotypes and functions.

Question 5

Types of cell lines

Answer 5

Continuous, Transformed, and Cancerous/Immortal

Question 6

Cerebral Spinal Fluid

Answer 6

Liquid within the ventricles of the brain and the subarachnoid spaces of the cranium and spine.

Question 7

Diagnostic test controls

Answer 7

Procedures used to ensure that reagents and lab instruments are working within predefined specifications, thereby safeguarding the reliability of test results.

Question 8

Diagnostic test reagent

Answer 8

Substances used in laboratories to determine specific
types of pathogens, metabolic abnormalities, physiological
anomalies, and genetic diseases.

Question 9

Fluorochrome

Answer 9

A chemical that fluoresces, especially one used as a label in biological tests and research

Question 10

Immunodiagnostic tests

Answer 10

based on interaction of antibody and antigen. ELISA and Serum Assays

Question 11

Molecular diagnostic tests

Answer 11

tests that analyze genome. PCR

Question 12

Precipitation

Answer 12

precipitation reaction is one in which dissolved substances in solution react to form one (or more) solid products. In immunodiagnostic precipitation tests, it is the
binding of antigen and antibody that form larger and larger Ag-Ab complexes that become large enough to precipitate
out of solution.

Question 13

Titer

Answer 13

A measure of the amount of a substance (such as an antibody) in a liquid sample that is obtained by subjecting the sample to serial dilutions (as with saline) to determine
the maximum dilution at which the sample retains a specific activity (such as neutralizing an antigen).

Question 14

Tumor antigens

Answer 14

Abnormal proteins produced by tumor cells that can trigger an adaptive immune response.