Lecture 12 Flashcards

(33 cards)

1
Q

What percentage of the body weight is water

A

60%

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2
Q

What are protein functions

A
  1. Structure
  2. Metabolism
  3. Transporter
  4. Maintaining fluid balance
  5. Contractile
  6. Neuronal
  7. Immune System
  8. pH Buffer
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3
Q

Where does protein structure come into play

A

Plasma membrane: integral and peripheral proteins
Collagen: Essential function in skin and connective tissue
Keratin: keeps skin, hair, and nails healthy and strong

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4
Q

Describe proteins role in metabolism

A

enzymes
transport across plasma membrane

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5
Q

Describe proteins role in Transport

A

hemoglobin
minerals
fatty acids
hormones
Ex) thyroxin

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6
Q

Describe proteins role in maintaining fluid balance

A

albumin in blood

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7
Q

Describe proteins contractile role

A

skeletal
cardiac
smooth muscles

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8
Q

Describe proteins role in neuronal

A

ion channels
signal transduction cascades

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9
Q

Describe proteins role in immune system

A

immunoglobins

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10
Q

Describe proteins role as a pH buffer

A

donating or accepting hydrogen ions (Zwitterions)

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11
Q

What is the Cα

A

Chiral carbon

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12
Q

All _____ ______, except ______, are ____________ (D and L forms) with ____ being the naturally occurring form in plant and animals

A

amino acids
glycine
stereoisomers
L

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13
Q

What type of chemical properties do R groups give amino acids

A

size
polarity
charge
bonding potential

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14
Q

What are the 4 main roles of amino acids

A
  1. building blocks of proteins
  2. Precursors of Neurotransmitters
  3. Precursors of Hormones
  4. Amino acids serve as pH buffers
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15
Q

how are amino acids used as building blocks of proteins

A

grown and development
repair of body tissues

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16
Q

how are amino acids used as precursors of Neurotransmitters

A

Biogenic amines
*catecholamines –> Tyrosine
*Indoleamines –> Tryptophan
* Histamine –> Histidine

17
Q

how are amino acids used as precursors of hormones

A

Thyroid hormones –> Tyrosine

18
Q

how are amino acids used as pH buffer

A

as Zwitterions
donate or accept protons preventing drastic pH changes

19
Q

what bonds link amino acids

A

peptide bonds

20
Q

What are molecular Chaperones

A

class of proteins that assist in protein folding into their correct 3D shapes

21
Q

What are the most common amino acids in αhelical structures

22
Q

What are the most common amino acids in βpleated sheets

23
Q

What are essential amino acids

A

Cannot be synthesized by the body
must be supplied by diet
Essential in Adults: ILKMFTYV
Essential in children, not in healthy adults: Histidine

24
Q

What are nonessential amino acids

A

can be synthesized by the body
Arginine

25
What are conditional amino acids
may or may not be needed depending on situations Ex) in illness, stress, or in developmental stages
26
What are essential amino acids for domestic dogs and cats
Dogs: Histidine and arginine Cat: Taurine
27
Describe AA in Legumes
Rich in Lysine and Tryptophan
28
Describe AA in Corn
deficient in Lysine and Tryptophan
29
Describe AA in Wheat
lacks essential Lysine, Threonine, Methionine
30
What provides a balances amino acid profile
Quinoa
31
What is deamination
removing an amino acid to form ammonia and a keto acid final step to eliminate excess nitrogen
32
What is Transamination
transfers an amino group from an AA to a keto acid Forming a new AA and a new keto acid
33
Describe the TCA cycle
Amphibolic