What percentage of the body weight is water
60%
What are protein functions
Where does protein structure come into play
Plasma membrane: integral and peripheral proteins
Collagen: Essential function in skin and connective tissue
Keratin: keeps skin, hair, and nails healthy and strong
Describe proteins role in metabolism
enzymes
transport across plasma membrane
Describe proteins role in Transport
hemoglobin
minerals
fatty acids
hormones
Ex) thyroxin
Describe proteins role in maintaining fluid balance
albumin in blood
Describe proteins contractile role
skeletal
cardiac
smooth muscles
Describe proteins role in neuronal
ion channels
signal transduction cascades
Describe proteins role in immune system
immunoglobins
Describe proteins role as a pH buffer
donating or accepting hydrogen ions (Zwitterions)
What is the Cα
Chiral carbon
All _____ ______, except ______, are ____________ (D and L forms) with ____ being the naturally occurring form in plant and animals
amino acids
glycine
stereoisomers
L
What type of chemical properties do R groups give amino acids
size
polarity
charge
bonding potential
What are the 4 main roles of amino acids
how are amino acids used as building blocks of proteins
grown and development
repair of body tissues
how are amino acids used as precursors of Neurotransmitters
Biogenic amines
*catecholamines –> Tyrosine
*Indoleamines –> Tryptophan
* Histamine –> Histidine
how are amino acids used as precursors of hormones
Thyroid hormones –> Tyrosine
how are amino acids used as pH buffer
as Zwitterions
donate or accept protons preventing drastic pH changes
what bonds link amino acids
peptide bonds
What are molecular Chaperones
class of proteins that assist in protein folding into their correct 3D shapes
What are the most common amino acids in αhelical structures
MALEK
What are the most common amino acids in βpleated sheets
THYVI
What are essential amino acids
Cannot be synthesized by the body
must be supplied by diet
Essential in Adults: ILKMFTYV
Essential in children, not in healthy adults: Histidine
What are nonessential amino acids
can be synthesized by the body
Arginine