psychatric pharma

Question 1

anti psycotic agents+ clincal use +moa?

Answer 1

typical (azian) + halo + primzide

atypical ( ioden+ zapin ) airpiperazole

schezo pos symptoms== typical
schezio neg and pos symptoms = atypical
psycosis + huntgtion + teretto +ocd

Block dopamine D 2 receptor ( cAMP). Atypical antipsychotics also block serotonin 5-HT 2 receptor. Aripiprazole is a D 2 partial agonist.

Question 2

anti psycotic SE?

Answer 2

3 anti == muscrinc (dry mouth constipation) + histamine (sedation)+ anti a adenrgic( hypotension)

metabolic == increasing lipid + glucose + wight gain

cvs = qt prolongation
cns = nuroleptic malignat
endocrine= hyper prolactinemis
clozapine= agranuloctosis+ myocarditis+ sizuer
extra pyramidal :
ADAPT
acut dystonia
aknathsia + parkinsonism+ terda dyskinasia

Question 3

antidepressent agent //moa// ?

Answer 3

Selective serotonin reuptake inhibitors(((Inhibit 5-HT reuptake.)))
Fluoxetine, fluvoxamine, paroxetine, sertraline, escitalopram, citalopram.((pram or ine))

Serotoninnorepinephrine reuptake inhibitors((( Inhibit 5-HT and NE reuptake.)))
Venlafaxine, desvenlafaxine, duloxetine, levomilnacipran, milnacipran.

Question 4

antidepressent SE

Answer 4

snri=  BP, stimulant effects, sedation, sexual dysfunction, nausea

ssri= Fewer than TCAs. Serotonin syndrome,
GI distress, SIADH, sexual dysfunction mania precipitation.

Question 5

tricyclic antidepressent agents+moa

Answer 5

امين /ابين/ الين
amine + apine+ aline

TCAs inhibit 5-HT and NE reuptake.

Question 6

Monoamine oxidase inhibitors agents + clincal uses ?

Answer 6

((Tranylcypromine, phenelzine, isocarboxazid, selegiline))
Nonselective MAO inhibition dopamine).
increases levels of amine neurotransmitters (norepinephrine, 5-HT,dopamin)

Question 7

monooxidase inhibiters SE?

Answer 7

CNS stimulation; hypertensive crisis, most notably with ingestion of tyramine.
ممنوع ينعطى مع anti depressent ثاني

Question 8

Atypical antidepressants agents + moa?

Answer 8

bupropion + Vortioxetine +zapin + zodone

zodone=blocks 5-HT2, α1-adrenergic, and H 1receptors; also weakly inhibits 5-HT reuptake

zapine= a2 antagonist inhibiting ne+ serotonin reuptake

Vortioxetine= inhibiting serotonin uptake
bupropion= ne + dopamine uptake

Question 9

atypical antidepresent SE ?

Answer 9

nusua + sadation+ anti coline dry mouth + hypotension

Question 10

Buspirone moa / clincal use

Answer 10

Partial 5-HT 1Areceptor agonist
فقط للgenrlized anxity disorder

Question 11

Lithium moa / clincal use

Answer 11

Affects neurotransmission (decreas excitatory,increas inhibitory) and second messenger systems (eg, G proteins).

mood stbilizer

Question 12

lithum SE

Answer 12

Tremor, ممنوع تعطيه مع المدرات يخرج من الكلى فقط ممكن ياثرو عليه
hormon:hypothyroidism, hyperthyroidism,
renal:mild hypercalcemia, polyuria (causes nephrogenic diabetes insipidus), teratogenesis