Endotoxin testing.

Question 1

What are endotoxin tests?

Answer 1

They are critical in vitro safety tests used to detect and quantify pyrogenic bacterial contaminants in pharmaceutical products, medical devices and water.

Question 2

What are the endotoxin tests?

Answer 2

There is the LAL reaction where LAL is added and clots in the presence of endotoxins. There is the LAL equivalent recombinant cascade reagent test using Factor C, B and pro-clotting enzyme to mimic the standard reaction. There is the gel clot method where LAL lysate is added to a tube with a sample and incubated at 37 degrees for 60 minutes to observe any clotting. There are detection assays for greater efficiency.