Anticholinergic
Opposites the effects of acetylcholine at acetylcholine receptor sites
Also known s as parasympathetic agents as their action lyses or blocks the effects of PNS.
Class of drugs was once widely used to decrease gastrointestinal (GI) activity and secretions in the treatment of ulcers and to decrease other parasympathetic activities to allow the sympathetic system to become more dominant.
PNS Blockage Symptoms
Parasympathetic failure or part of a broader dysautomonia, results in the loss of the bodies rest and digest functions.
Leave SNS system unopposed leading to symptoms of rapid HR, severe constipation, dry eyes/mouth and urinary rention.
Anticholinergic Agents: other uses
Bronchodilation and treatment of overactive bladder
Atropine
Derived for the belladonna plant
Widely used anticholinergic drug used to treat symptomatic bradycardia, antidote for cholinergic medications, to cause pupil dilations and to decrease secretions in
Flavoxate
Anticholinergics
Symptoms relief of dysuria, urengey, nocturia, Supra pubic pain, freq and inc associated with cystitis, Prostatitis, urethritis, urethrocysiutis or urethrotrigonitis
Atropine Drug
To decrease secretions before surgery; treatment of parkinsonism; restoration of cardiac rate and arterial pressure following vagal stimulation; relief of bradycardia and syncope due to hyperactive carotid sinus reflex; relief of pylorospasm; relaxation of the spasm of biliary and ureteral colic and bronchospasm; control of crying and laughing episodes associated with brain lesions; relaxation of uterine hypertonicity; management of peptic ulcer; control of rhinorrhea associated with hay fever; antidote for cholinergic overdose; and poisoning from various mushrooms.
Actions: Competitively blocks acetylcholine muscarinic receptor sites, blocking the effects of the parasympathetic nervous system.
Ipratropium
Maintenance treamtn of broncspasm associated with COPD, nasal spray for symptomatic relief of perennial and seasonal rhinitis