Use Nurs 316 Notes: Unit 5
Anti-Infective Action on Cells
Designed to target foreign organism that have invaded and infected the body of a host.
Act on cells by preventing it from reproducing and to cause cell death without affecting host cells.
Drug Therapy Across the Lifespan: Peds
Anti-Infective Agents
Use anti-infectives with caution; early exposure can lead to early sensitivity.
Controversy is widespread regarding the use of antibiotics to treat ear infections, a common pediatric problem. Some believe that the habitual use of antibiotics for what might well be a viral infection has contributed greatly to the development of resistant strains.
Because children can have increased susceptibility to anti-infectives’ effects on the gastrointestinal (GI) and nervous systems, carefully monitor their hydration and nutritional status.
Treatment of Systemic Infections
These factors include identification of the correct pathogen and selection of a drug that is most likely to (a) cause the fewest complications for that patient and (b) be most effective against the pathogen involved.
Identitifaction of the pathogen
is done by culturing a tissue sample from the infected area.
Cultures are performed in a laboratory, in which a swab of infected tissue is allowed to grow on an agar plate. Staining techniques and microscopic examination are used to identify the offending pathogen.
Parasitic sources of infection, they may examine stool for ova and parasites.
Microscopic examination of other samples is also used to detect fungal and protozoal infections.
Sensitivity of the Pathogen
use a broad-spectrum anti-infective agent that has been shown to be most effective in treating an infection with certain presenting signs and symptoms.
In other cases of severe infection, a broad-spectrum antibiotic is started after a culture is taken but before the exact causative organism has been identified.
Sensitivity testing is done to evualte the bacteria and detemined the drug
Combination Therapy
a combination of two or more types of drugs will effectively treat the infection. When the offending pathogen is known, combination drugs may be effective in interfering with its cellular structure in different areas or developmental phases.
Antiprotozoals
For infections caused by specific Protozoa
Includes: malaria
Anthelmontic
Used for infections caused by by worms
Such as tapeworms and roundworms without harming the host