What is metastatic calcification?
Calcium deposits in healthy cells and tissues due to hypercalcaemia
Causes of hypercalcaemia (4)
Which tissues are most affected by metastatic calcification?
tissues that secrete acid and have and internal alkaline pH : kidney, stomach, lung
Severe cases of metastatic calcification?
- nephrocalcinosis
Why is there high calcium in renal failure?
phosphate is not secreted but retended so there is low serum calcium - so parathyroid produces parathromone to raise calcium levels